Two New Arylnaphthalide Lignans from Justicia flava Roots*

Abstract

Orosunol and 8-demethylorosunol, two new 1-aryl-2,3-naphthalide lignans, have been isolated from Justicia flava root. Structures IV and V respectively have been proposed for them by spectral (UV, IR, PMR, (13)C NMR, and MS) and chemical evidence.

Bioactive Compounds from Taiwania cryptomerioides

“…Three additional known compounds, R-cadinol 11 (4), ferruginol, 12 and helioxanthin, 13 were also isolated and identified based on the complete agreement of their spectral data with those reported in the literature. 21.3* q 21.5* q 21.4* q 15 28.7 q 28.2 q 26.2 q a Items marked with asterisks within the same column are interchangeable.…”

“…Isolate 3 was identified as 10R-hydroxycadinan-4-en-3-one, which was originally isolated from this plant but not reported with detailed 1 H-and 13 C-NMR data. 2 The 1 H-NMR assignments for 3 are presented in Table 1 and are based on the COSY spectrum.…”

“…Compound 1 was isolated as an oil, and its molecular formula, C 15 H 24 O 2 , was determined by analyzing its HREIMS molecular ion at m/z 236.1776 (calcd 236.1776). The 13 C-NMR spectrum of 1 showed 15 carbon signals, including one carbonyl, one double bond, one oxygenated carbon, three methylenes, four methines, and four methyl groups. A downfield broad singlet at δ 6.95 (H-5) in its 1 H-NMR spectrum indicated the presence of a double bond conjugated with a carbonyl group.…”

“…2 The 1 H-NMR assignments for 3 are presented in Table 1 and are based on the COSY spectrum. 13 C-NMR data for 3 are shown in Table 2. The relative stereochemistry of 3 was confirmed by the correlations observed in its NOESY spectrum.…”

Antimicrobial Importance of Medicinal Plants in Nigeria

“…In a study on antifungal activity of C . procera , there was complete inhibition of Microsporum and Trichophyton species after ten days of inoculation with water extract at different concentrations [ 88 ].…”