Two new C-benzylated chalcones and one new mimosin-type homoisoflavonoid from the twigs and leaves of Caesalpinia digyna

Qin, Haobei; Bi, De-Wen; Li, Fengqiu; Luo, Ruilong; Zhuang, Hongdan; Wang, Liqin

doi:10.1016/j.fitote.2022.105279

Fitoterapia

2022

DOI: 10.1016/j.fitote.2022.105279

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Two new C-benzylated chalcones and one new mimosin-type homoisoflavonoid from the twigs and leaves of Caesalpinia digyna

Haobei Qin

De-Wen Bi

Fengqiu Li

et al.

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2024

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Cited by 4 publications

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“…Figure 17. New flavonoids chemical structures.Two new C-benzylated chalcones were obtained from the twigs and leaves of Caesalpinia digyna Rottler (Fabaceae) and were identified as 2′,4′-dihydroxy-3′-(2-hydroxylbenzyl) chalcone and 2′,4′-dihydroxy-5′-(2-hydroxybenzyl) chalcone (79)[122]. Both compounds showed cytotoxicity against SMMC-7721, A-549, and MDA-MB-231 cell lines.…”

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confidence: 99%

New Compounds from Terrestrial Plants: A Perspective View

Oliveira,

Kohatsu,

Hufnagel

et al. 2024

Compounds

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In an era where the search for innovative drug leads faces challenges, our study pivots towards exploring the untapped potential of plant-derived compounds, focusing on the period of 2021 to 2022. We assess the classes of compounds these new structures belong to; the plants and families these compounds belong to; and the degree of novelty of the compound compared with already-known structures. The review was conducted following the Preferred Reporting Items for Systematics Reviews and Meta-Analyses (PRISMA) statement checklist for the guided reporting of systematic reviews. A total of 464 articles were selected for the new compounds of natural origin survey. We included 117 complete articles in this review and reported approximately 109 new structures elucidated during the years 2021 and 2022. Many of the compounds showed small structural variations in relation to already-known molecules. For some, however, this small modification was decisive for the biological activity reported, demonstrating the importance of descriptive phytochemical studies.

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confidence: 99%

New Compounds from Terrestrial Plants: A Perspective View

Oliveira,

Kohatsu,

Hufnagel

et al. 2024

Compounds

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Caesalpinflavans D-F and caesalpinnone B, hybrid flavan-chalcones and normonoterpene-chalcone heterodimer from Caesalpinia digyna

Duan,

Qin,

et al. 2024

Phytochemistry

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Isolation and characterization of dihydrohomoisoflavonoids from Portulaca oleracea L.

Liu,

Wang,

Shao

et al. 2024

Phytochemistry

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Two new C-benzylated chalcones and one new mimosin-type homoisoflavonoid from the twigs and leaves of Caesalpinia digyna

Cited by 4 publications

References 11 publications

New Compounds from Terrestrial Plants: A Perspective View

New Compounds from Terrestrial Plants: A Perspective View

Caesalpinflavans D-F and caesalpinnone B, hybrid flavan-chalcones and normonoterpene-chalcone heterodimer from Caesalpinia digyna

Isolation and characterization of dihydrohomoisoflavonoids from Portulaca oleracea L.

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