Two new dimethylpyranoflavanones from the roots of
            <i>Melodorum fruticosum</i>

A new pregnane steroid, jasminanthoside (1), together with three known compounds, telosmoside A7 (2), syringaresinol (3), and methyl 6-deoxy-3-Omethyl-β-D-allopyranosyl-(14)-β-D-oleandropyranoside (4) were isolated from the ethyl acetate extract of Jasminanthes tuyetanhiae roots collected in Vietnam.Their chemical structures were elucidated by NMR and MS spectroscopic data analysis along with the comparison of their data with the published ones in the literature. Although 4 was a known compound, its full NMR data were reported for the first time. All isolated compounds, evaluated for their α-glucosidase inhibition, showed activities stronger than the positive control acarbose. Among them, 1 was the best with the IC50 value of 7.41 ± 0.59 µM.

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New prenyl flavanone and diarylbutanol from Uvaria siamensis stem bark and their α -glucosidase inhibitory activity

Nguyen,

Ngo,

Nguyen

et al. 2023

Natural Product Research

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Two new dimethylpyranoflavanones from the roots of Melodorum fruticosum

Cited by 3 publications

References 18 publications

A New Lanostane-Type Triterpene from the Branches of Thai Uvaria siamensis

A New Lanostane-Type Triterpene from the Branches of Thai Uvaria siamensis

Jasminanthoside – a new pregnane-steroid from Jasminanthes tuyetanhiae

New prenyl flavanone and diarylbutanol from Uvaria siamensis stem bark and their α -glucosidase inhibitory activity

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