Two new flavanonol glycosides from Gordonia chrysandra

Wang, Kun; Yang, Jing Zhi; Zuo, Li; Zhang, Dong Ming

doi:10.1016/j.cclet.2007.10.033

Cited by 17 publications

(5 citation statements)

References 3 publications

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“…Data spektrum IR memberikan serapanserapan yang khas untuk beberapa gugus fungsi. Serapan pada bilangan gelombang 1638 cm -1 adalah khas untuk gugus karbonil terkhelat dengan OH yang didukung pula oleh serapan pada υ maks 3403 cm -1 melebar yang menunjukkan vibrasi OH berikatan hidrogen; serapan pada υ maks 1603, 1513, 1450 cm -1 merupakan serapan khas untuk ikatan rangkap pada cincin aromatik, dimana data-data ini menguatkan data dari spektrum UV, sedangkan serapan pada υmaks 2924 cm -1 menunjukkan adanya C-H alifatik (Wang et al 2008).…”

Section: Hasil Dan Analisa Spektroskopi Infra Redunclassified

“…Dari analisa data spektrum UV dan IR maka dapat disarankan bahwa senyawa (1) merupakan flavanon atau flavanonol yang memiliki gugus hidroksil pada posisi orto dan para dari gugus karbonil (Mabry et al 1970;Wang et al 2008). Hal ini diperkuat oleh spektrum UV senyawa ini dalam metanol yang memperlihatkan serapan pita I dan pita II yang khas untuk senyawa flavonoid, dimana kekuatan serapan dapat memberikan informasi tentang jenis flavonoid.…”

Section: Hasil Dan Analisa Spektroskopi Infra Redunclassified

“…Hal ini diperkuat oleh spektrum UV senyawa ini dalam metanol yang memperlihatkan serapan pita I dan pita II yang khas untuk senyawa flavonoid, dimana kekuatan serapan dapat memberikan informasi tentang jenis flavonoid. Kekuatan serapan pita I yang lebih rendah daripada pita II adalah sesuai untuk flavonoid dengan kerangka flavanon dan flavanonol (Mabry et al 1970;Wang et al 2008).…”

Section: Hasil Dan Analisa Spektroskopi Infra Redunclassified

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Aktivitas Antimalaria GB-1a Kayu Akar Garcinia xanthochymus Hook.F.ex.T.Anderson

Wahyuningsih

2018

Chim. Nat. Acta

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Abstrak: Pada penelitian ini dihasilkan senyawa biflavonoid, GB-1a (1) dari kayu akar Garcinia xanthochymus Hook.f.ex.T.Anderson, Kebun Raya Bogor, Jawa Barat.Senyawa ini dipisahkan dari ekstrak metanol dengan metode ekstraksi maserasi, kemudian dilanjutkan dengan fraksinasi menggunakan kromatogrfi cair vakum (KCV), Kromatografi Kolom Gravitasi (KKG) dan pemurnian dilakukan dengan kromatografi radial. Elusidasi struktur molekul senyawa dilakukan berdasarkan data spektroskopi UV, IR, 1 H dan 13 C-NMR. Selanjutnya hasil uji aktivitas antimalaria menggunakan parasit Plasmodium falciparum strain 3D7 menunjukkan aktivitas yang moderat dengan harga IC 50 0,34µg/mL (1). -1a (1) were produced from the root wood of Garcinia xanthochymus Hook.f.ex.T.Anderson, Botanical Garden Bogor, West Java. This compound was separated from methanol extract by maceration extraction method, then continued with fractionation using vacuum liquid chromatography (KCV), Gravity Column Chromatography (KKG) and purification was carried out by radial chromatography. Elucidation of the molecular structure of the compounds was carried out based on UV, IR, 1 H and 13 C-NMR spectroscopic data. Furthermore, the results of antimalarial activity tests using the Plasmodium falciparum strain 3D7 parasite showed moderate activity at a price of IC 50 0.34 µg / mL (1) Abstract: In this study biflavonoid compounds, GB

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Section: Hasil Dan Analisa Spektroskopi Infra Redunclassified

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Aktivitas Antimalaria GB-1a Kayu Akar Garcinia xanthochymus Hook.F.ex.T.Anderson

Wahyuningsih

2018

Chim. Nat. Acta

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“…Sub-frame is the main component of dump truck, its stiffness and strength affects the life of the vehicle, the level of technology and the evaluation of user directly. Therefore, strength analysis of the sub-frame has practical significance [1] .…”

Section: Introductionmentioning

confidence: 99%

Static Analysis of the Sub-Frame Based on Precision Load

Wang

2014

AMM

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In this paper, strength analysis of the sub-frame of a heavy-duty dump truck was done based on ADAMS and ANSYS. A prototype model of dump system of dump truck was built basis of drawings and technical documents. The prototype model of dump system was imported into ADAMS, then driving and kinematic pair were created to form a complete prototype system. Force curve and force value of each key point in the sub-frame was obtained under unloaded condition by simulation of unloading operation. The results showed that the strength and stiffness of the sub-frame under pure bending condition and the initial stage of unloaded condition meet the requirements;In critical slipped stage of cargo, the maximum stress of the rear rotating shaft of sub-frame is greater than the yield limit of the materials, and its position is consistent with fault location in the practical application.

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“…Phytochemical studies on these plants have led to the isolation and identification of triterpenoids [1][2][3][4], steroids [5], tannins [6], and several other components [7]. Moreover, our previous investigations on the roots and stems of Gordonia chrysandra Cowan have provided a diverse array of new saponins and flavonoids, with a range of bioactivities such as cytotoxic [8], anti-inflammatory, and hepatoprotective properties [9,10]. As a continuation of this study, we focused on another species, Gordonia longicarpa Chang, which is distributed in southern mainland China, northern Vietnam, and Cambodia.…”

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confidence: 99%

Cytotoxic Triterpenoid Saponins from the Stems of Gordonia longicarpa

Jia

et al. 2013

Planta Med

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Nine new triterpenoid saponins named longicarposides A-I (1-9), together with three known saponins (10-12), were isolated from the stems of Gordonia longicarpa. The structures of the saponins were elucidated by a combination of 1D and 2D NMR techniques, mass spectrometry, and chemical methods. They were characterized to be oleanane-type saponins with sugar moieties linked to C-3 of the aglycone. Cytotoxic activities of these saponins were evaluated against five human tumor cell lines (HCT-8, Bel-7402, BGC-823, A549, and A2780) by using the MTT in vitro assay. Compounds 5, 7, 8, 10, and 11 exhibited potent cytotoxic activity with IC50 values of 1.42-8.42 µM, while 6, 9, and 12 showed selective cytotoxic activity toward the tested cell lines.

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Two new flavanonol glycosides from Gordonia chrysandra

Cited by 17 publications

References 3 publications

Aktivitas Antimalaria GB-1a Kayu Akar Garcinia xanthochymus Hook.F.ex.T.Anderson

Aktivitas Antimalaria GB-1a Kayu Akar Garcinia xanthochymus Hook.F.ex.T.Anderson

Static Analysis of the Sub-Frame Based on Precision Load

Cytotoxic Triterpenoid Saponins from the Stems of Gordonia longicarpa

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