Two new simple iridoids from the ant-plant <i>Myrmecodia tuberosa</i> and their antimicrobial effects

Hạnh, Nguyễn Văn; Phan, Nguyen Huu Toan; Thuan, Nguyen Thi; Hạnh, Trần Thị Hồng; Vien, Le Thi; Thảo, Nguyễn Phương; Thành, Nguyễn Văn; Cuong, Nguyen Xuan; Bình, Nguyễn Ngọc; Nam, Nguyễn Hoài; Kiệm, Phan Văn; Kim, Young Ho; Minh, Châu Văn

doi:10.1080/14786419.2015.1113412

Cited by 11 publications

(9 citation statements)

References 8 publications

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“…Meanwhile, people in Mindanao-Philippines used fresh tubers of this species to treat several diseases such as goiter, stomachache, and fever [18]. In Vietnam, M. tuberosa was used as a folk medicine to treat hepatitis [19]. Another species of Myrmecodia genus Myrmecodia platytyrea Becc.…”

Section: Traditional Usesmentioning

confidence: 99%

“…The widespread use of the Myrmecodia genus has resulted in the phytochemical constituent analysis of different species. Based on a phytochemical screening test, generally, the hypocotyl of the Myrmecodia genus contained flavonoid, tannin, saponin, glycoside, carbohydrates, and quinone [4], alkaloids [18], iridoid [19], [25], steroid/ triterpenoid [26], diterpenoid [27], phenolics [28], and polyphenolics [29], [30]. The phytochemical screening showed the major compounds of Myrmecodia species are phenolic and flavonoid (Figure 1).…”

Section: Phytochemistrymentioning

confidence: 99%

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Medicinal Properties of Ant Nest Plant (Myrmecodia Genus): A Comprehensive Review

Dirgantara

Insanu

Fidrianny

2022

Open Access Maced J Med Sci

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BACKGROUND: The Myrmecodia genus belongs to the Rubiaceae family, which has the characteristic of an epiphytic plant. This genus spread from Malaysia, through the Philippines, Sumatra, Borneo, Java, New Guinea (Papua), Cape York to the Solomon Islands and Pacific region. It has been empirically proven to treat gout, inflammation, muscle pain relief, strengthen the body’s immunity, and cancer treatment. AIM: This article reviewed the scientific work about the Myrmecodia genus concerning their traditional uses, phytochemical compounds, and pharmacological activities of Myrmecodia. METHODS: The sources were from the scientific literature online database, including Science Direct, PubMed, and Google Scholar between 1978 and 2021. Furthermore, 112 articles were collected, while 61 full-text were assessed for eligibility. RESULTS: The Myrmecodia extract has many pharmacological activities, namely antioxidant, antibacterial, cytotoxic, and anticancer. CONCLUSION: Moreover, this review may be used as scientific literature for the next investigations on the genus Myrmecodia, especially regarding pharmacological properties such as in vitro and in vivo studies and isolation of the active compounds.

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Section: Traditional Usesmentioning

confidence: 99%

Section: Phytochemistrymentioning

confidence: 99%

Medicinal Properties of Ant Nest Plant (Myrmecodia Genus): A Comprehensive Review

Dirgantara

Insanu

Fidrianny

2022

Open Access Maced J Med Sci

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“…In the Rubiaceae, the organic polar and mid-polar extracts of Guettarda speciosa L., Hydnophytum formicarum Jack, Morinda citrifolia L., and Myrmecodia tuberosa Jack, and Guettarda speciosa L. are antibacterial and antifungal [ 82 , 225 , 226 , 227 , 228 ] ( Table S2 ) [ 81 , 162 , 229 , 230 , 231 ]. Plants in this family yield antimicrobial water soluble iridoid glycosides such as in loganic acid ( 67 ) from G. speciosa, which strongly repressed HCV [ 228 ], and asperuloside ( 68 ) from M. citrifolia ( Table S2 ) [ 77 , 91 , 93 , 220 , 232 , 233 , 234 ].…”

Section: Distribution Of Antibacterial Antifungal and Antiviral Princ...mentioning

confidence: 99%

Antimicrobial Secondary Metabolites from the Mangrove Plants of Asia and the Pacific

et al. 2022

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Microbes such as the White Spot Syndrome Virus account for severe losses in the shrimp farming industry globally. This review examines the literature on the mangrove plants of Asia and the Pacific with antibacterial, antifungal, or antiviral activities. All of the available data published on this subject were collected from Google Scholar, PubMed, Science Direct, Web of Science, ChemSpider, PubChem, and a library search from 1968 to 2022. Out of about 286 plant species, 119 exhibited antimicrobial effects, and a total of 114 antimicrobial natural products have been identified including 12 with MIC values below 1 µg/mL. Most of these plants are medicinal. The mangrove plants of Asia and the Pacific yield secondary metabolites with the potential to mitigate infectious diseases in shrimp aquaculture.

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“…Myrmecodia tuberosa Jack which is also known as antnest is an epiphytic plant with high antioxidant activity and medical value (Hertiani et al 2010;Soeksmanto et al 2010;Hanh et al 2016). Generally, it is often used as a traditional medicine such as a health supplement for the mother's recovery after childbirth and during breastfeeding (Firdausy and Nurlaila 2016).…”

Section: Introductionmentioning

confidence: 99%

Growth performance and blood profiles of striped catfish (Pangasianodon hypophthalmus) fed leaves extract of Myrmecodia tuberosa

et al. 2019

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Abstract. Nugroho RA, Hardi EH, Sari YP, Aryani R, Rudianto. 2019. Growth performance and blood profiles of striped catfish (Pangasianodon hypophthalmus) fed leaves extract of Myrmecodia tuberosa. Nusantara Bioscience 11: 89-96. The application of plant extract in the aquaculture field is gaining momentum. This study aimed to determine the effects of M. tuberosa Jack leaves extract on the growth performance and blood profiles of striped catfish (Pangasianodon hypophthalmus). 400 fish with an initial average weight of 1.54 ± 0.02g were randomly divided into five groups and fed with different concentration of M. tuberosa Jack leaves extract (0.25, 0.5, 1, 2%) and control diet for 80 days. Growth performance, feed conversion rate, feed efficiency, survival rate, morphometric, and hematological profile of the fish were evaluated at the end of the trial. The results found that fish fed 0.5-1% concentration had significantly higher (P<0.05) growth, feed conversion rate, feed efficiency, morphometric value, survival, white blood cell, hemoglobin, neutrophil, lymphocyte, and monocyte than control. Meanwhile, supplementation of 2% MTE in the diet of fish reduced growth, feed utilization, viscerosomatic index, and morphometric values but increased red blood cell. All the supplemented diets decreased platelet of fish. The findings indicated that supplementation 0.5-1% of MTE is beneficial to the growth and blood profile of fish through the increment of growth indices, feed utilization, white blood cell, hemoglobin, neutrophil, lymphocyte, and survival rate of fish.

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Two new simple iridoids from the ant-plant Myrmecodia tuberosa and their antimicrobial effects

Cited by 11 publications

References 8 publications

Medicinal Properties of Ant Nest Plant (Myrmecodia Genus): A Comprehensive Review

Medicinal Properties of Ant Nest Plant (Myrmecodia Genus): A Comprehensive Review

Antimicrobial Secondary Metabolites from the Mangrove Plants of Asia and the Pacific

Growth performance and blood profiles of striped catfish (Pangasianodon hypophthalmus) fed leaves extract of Myrmecodia tuberosa

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