Two novel aporphine-derived alkaloids from the stems of Fissistigma glaucescens

Fu, Liang; Dai, De-Cai; Yang, Rui; Chen, Guang‐Ying; Zheng, Cai‐Juan; Xia, Song; Zhou, Xue-Ming

doi:10.1016/j.fitote.2021.105036

Fitoterapia

2021

DOI: 10.1016/j.fitote.2021.105036

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Two novel aporphine-derived alkaloids from the stems of Fissistigma glaucescens

Liang Fu

De-Cai Dai²,

Rui Yang

et al.

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Cited by 7 publications

References 19 publications

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Bioactive 5/5/5/6 Four–Ring System Iridoids from Plumeria alba L.

Zhou,

Meng,

Zhou

et al. 2024

Chemistry & Biodiversity

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Two rare 5/5/5/6 four‐ring system iridoids, allamancins A and B (1 and 2) together with one known biogenetically related iridoid derivative, 3‐O‐methyallamancin (3) were isolated from the flowers of Plumeria alba L. The structures of these iridoid derivatives were determined by comprehensive spectroscopic analyses. The absolute configuration of 1 was confirmed by X‐ray crystallographic analysis. The inhibitory activities of compounds 1‐3 against nitric oxide (NO) production induced and three cancer cell lines were evaluated in vitro. Compounds 1 and 3 showed inhibitory activities on NO production with IC50 values of 18.3 ± 0.12 and 22.1 ± 0.14 µM, respectively. Compounds 1‐3 showed moderate inhibitory activities against cancer cell lines of A549, Hela and MCF‐7.

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Bioactive 5/5/5/6 Four–Ring System Iridoids from Plumeria alba L.

Zhou,

Meng,

Zhou

et al. 2024

Chemistry & Biodiversity

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Biologically active isoquinoline alkaloids covering 2019–2022

Wang,

Qin,

Jing

et al. 2024

Bioorganic Chemistry

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Phenolic and sesquiterpene derivatives from Fissistigma retusum

Wang

Dai²,

et al. 2022

Biochemical Systematics and Ecology

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Two novel aporphine-derived alkaloids from the stems of Fissistigma glaucescens

Cited by 7 publications

References 19 publications

Bioactive 5/5/5/6 Four–Ring System Iridoids from Plumeria alba L.

Bioactive 5/5/5/6 Four–Ring System Iridoids from Plumeria alba L.

Biologically active isoquinoline alkaloids covering 2019–2022

Phenolic and sesquiterpene derivatives from Fissistigma retusum

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