In an era of climate change, biodiversity loss, and a global pandemic, many scientists have experienced grief, anxiety, and despair as they face ongoing ecological challenges. The practice of conservation science has also become contentious in light of increasingly polarized viewpoints and conflicts among stakeholders. These ecological and social challenges may hinder conservation scientists' ability to identify critical science needs that can inform and improve conservation policies, actions, and outcomes. Mindfulness practices provide a centering framework that supports scientists in addressing these challenges while also fostering meaningful collaborations with other conservation scientists and practitioners. In this paper, we synthesize theories from mindfulness and attitudinal foundations that offer practical steps toward the kind of resilient mindset needed to address challenges flexibly and from a solutions-driven perspective. By cultivating equanimity, gratitude and hope, mindfulness practices bring understanding and empathy to collaborative activities, improving our collective ability to generate meaningful science that addresses pressing environmental challenges.