We study the influence of broken connectivity and frequency disorder in systems of coupled neuronal oscillators. Under nonlocal coupling, systems of nonlinear oscillators, such as Kuramoto, FitzHugh-Nagumo or Integrate-and-Fire oscillators, demonstrate nontrivial synchronization patterns. One of these patterns is the "chimera state", which consists of coexisting coherent and incoherent domains. In networks of biological neurons, the connectivity is not always perfect, but might be locally broken, or interrupted due to pathologies, neuron degenerative disorders or accidents. Our simulations show that destructed connectivity drastically affects synchronization, driving the coherent parts of the chimera state to cover symmetrically the region where the anomaly is located. The network synchronization decreases with the size of the destructed region as evidenced by the Kuramoto synchronization index. To the contrary, when keeping the connectivity of all nodes intact, altering the frequency in a block of oscillators drives the incoherent part of the chimera state toward the anomaly. This work is in-line with recent dynamical approaches aiming to locate anomalies in the structure of brain networks, in particular when the anomalies have small, difficult-to-detect sizes.