Two Rare Cases of Tumor Calcinosis

Abstract

Tumour calcinosis is a rare disorder of phosphate metabolism. Familial tumour calcinosis is caused due to gene mutations affecting the activity of FGF23, a phosphoturic hormone. The presentation is hyperphosphatemia and calcified deposits in the periarticular regions. Surgery though being the mainstay of treatment, recurrence is often common without additional treatment. Phosphate restricted diet and phosphate binder before and after surgery would be beneficial. We present two cases of tumour calcinosis with hyperphosphatemia and calcified deposits, evaluated and followed up. We discuss various treatment options available for this rare condition