2014
DOI: 10.1186/1746-1596-9-27
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Two rare schwannomas of head and neck

Abstract: Twenty-five to 45 percent of all schwannomas occur in the head and neck. Most of them arise along the vestibular portion of the eighth cranial nerve (acoustic neurinoma). They rarely originate from the peripheral facial nerve or other nerves within the parotid gland. Less than 4% of schwannomas involve the nasal cavity and paranasal sinuses. They arise from the branches of the trigeminal nerve and autonomic nervous system.We report two cases of schwannomas arisng from intraparotid facial nerve and nasal cavity… Show more

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Cited by 23 publications
(12 citation statements)
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“…Schwannoma originates from peripheral nerve sheath Schwann cells, grow slowly, having a complete envelope and a clear boundary. It usually grows expansively around the nerve, and the nerve bundle does not enter the inside of the tumor [2], it can occur in all parts of the body, most of which occur in the head and neck (25% to 45%) [3] , which is rare in the ear, nose and throat (4%). In this case, nasal endoscopy combined with navigation system was used during operation, improving the accuracy and safety of surgery.…”
Section: Discussionmentioning
confidence: 99%
“…Schwannoma originates from peripheral nerve sheath Schwann cells, grow slowly, having a complete envelope and a clear boundary. It usually grows expansively around the nerve, and the nerve bundle does not enter the inside of the tumor [2], it can occur in all parts of the body, most of which occur in the head and neck (25% to 45%) [3] , which is rare in the ear, nose and throat (4%). In this case, nasal endoscopy combined with navigation system was used during operation, improving the accuracy and safety of surgery.…”
Section: Discussionmentioning
confidence: 99%
“…Schwannomas of head and neck region are typically described as solitary encapsulated lesions that arise in the first o second division of the trigeminal nerve. On the contrary, when these tumors are multiple, they are typically found in Neurofibromatosis type 1, a disease associated to mutation at the NF1 gene [4]. Another form of neurofibromatosis was recently recognized, called schwannomatosis, and a case of bilateral maxillary sinus schwannomas in a patient with this disease was reported very recently in literature [10].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, differential diagnosis with rare malignant peripheral nerve sheath tumors is necessary. A contrast enhanced CT scan can evaluate the vascularisation of the lesion, but MRI with gadolinium is investigation of choice for identification and examination of the suspected nerve lesions of sinonasal cavity [4]. On an MRI scan, schwannomas appears with an intermediate signal intensity on T1-weighted images, whereas a T2weighted signal varies depending on the tumor structure [17].…”
Section: Discussionmentioning
confidence: 99%
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“…Histologically, schwannomas are characterized by broad interlacing ribbons of extended spindle cells that produce a palisading pattern of nuclei around a central mass of cytoplasm. Detection of S100 is required to establish the neural origin of the tumor ( 4 ). Anatomically, the majority of TSs arise from the Gasserian ganglion and spread to the intradural and epidural cavities ( 5 ).…”
Section: Introductionmentioning
confidence: 99%