Two-stage window screening and development trajectories in early identification of autism spectrum disorder among Han Chinese children

Lung, For‐Wey; Shu, Bih‐Ching

doi:10.1186/s13104-021-05548-1

Cited by 3 publications

(1 citation statement)

References 21 publications

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“…Previous studies of TBCS-DI have shown development at 1.5 years and later to be predictive of children's emotional, cognitive, and social-communicative development at age eight (Lung et al, 2020 ). However, when the diagnosis is put into context, children's developmental trajectories show that language development is unstable before 3 years, and therefore not suitable for ASD diagnosis (Lung and Shu, 2021 ).…”

Section: Discussionmentioning

confidence: 99%

Families with high-risk characteristics and diagnoses of attention-deficit/hyperactivity disorder, autism spectrum disorder, intellectual disability, and learning disability in children: A national birth cohort study

Lung

Chen²,

Shen³

et al. 2022

Front. Psychol.

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BackgroundA national birth cohort study was used to investigate whether high-risk family factors at 1.5-year-olds can increase the risk of attention-deficit/hyperactivity disorder (ADHD) diagnosis when children reach 5.5 years. The pathway relationship of high-risk family factors, children's developmental conditions, risk of autism spectrum disorder (ASD), and diagnosis of intellectual disability (ID), learning disability (LD), and ASD was also investigated.MethodsThe 1.5-, 3- and 5.5-year-old Taiwan Birth Cohort Study (TBCS) dataset was used (N = 19,185). The high-risk familial factor was measured using five questions assessing whether parents are currently unmarried, unemployed, do not have any social insurance, perceive a “very heavy” economic childcare burden, and at least one of the parents has a disability certification. Developmental conditions were assessed using the Taiwan Birth Cohort Study—Developmental Instrument (TBCS-DI), and ASD risk was measured using the Modified Checklist of Autism in Toddlers. Data on ADHD, ID, LD, and ASD diagnoses were collected at age 5.5. The odds ratio model investigated whether children from families with high-risk factors at 1.5-years were at increased risk of ADHD, ID, LD, or ASD diagnosis at 5.5-years, compared to those children from families without such risks. Structural equation modeling investigated the logistic regression pathway relationship of high-risk familial characteristics, children's developmental conditions, autism screening, and diagnosis.ResultsIn the national birth cohort dataset of 19,185 children, 2070 (10.8%) met at least one of the high-risk familial factors. Children who met one high-risk familial factor had a 1.21-fold increased risk for ADHD diagnosis, 1.36-fold increased risk for LD diagnosis, and 1.80-fold increased risk for ASD diagnosis, compared to children from families without risks. High-risk familial factors directly increased the risk of ADHD and ID diagnosis, and indirectly increased the risk of ADHD, ID, LD, and ASD diagnosis through the mediating factor of children's development.ConclusionsChildren who met more high-risk familial characteristics were at higher risk of ADHD, ID, LD, and ASD diagnosis. Development at three years was predictive of diagnosis at 5.5 years. Thus, developmental screening at age three is vital for interventions. Preventive, family-focused, and/or child-rearing services for at-risk families are important for improving outcomes for these children and their families.

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Section: Discussionmentioning

confidence: 99%

Families with high-risk characteristics and diagnoses of attention-deficit/hyperactivity disorder, autism spectrum disorder, intellectual disability, and learning disability in children: A national birth cohort study

Lung

Chen²,

Shen³

et al. 2022

Front. Psychol.

Self Cite

View full text Add to dashboard Cite

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Urban–Rural Disparity in the Incidence of Diagnosed Autism Spectrum Disorder in Taiwan: A 10-Year National Birth Cohort Follow-up Study

Hsu

Chen

Lin

et al. 2022

J Autism Dev Disord

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Characteristics for the diagnosis of Autism Spectrum Disorder

Lima Rocha,

Salguero

2025

AG Salud

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Introduction: autism Spectrum Disorder (ASD) is indeed a neurodevelopmental disorder whose exact cause is not yet fully understood. Symptoms can vary significantly among affected individuals, but generally include difficulties in communication and social interaction, as well as repetitive and restricted behaviors. Identification of early indicators and early diagnosis, as well as effective management of ASD, may lead to earlier and improved intervention in affected patients.Methods: a search for information on diagnostic indicators of ASD was conducted in Pubmed, Cochrane and clinicaltrials.org databases. Systematic reviews and meta-analyses were identified without considering publication status, reported results, last five years of publication and with language restriction to English, Spanish and Portuguese.Results: a total of 12 studies published between 2013 - 2023 were selected, and 7 systematic reviews and meta-analyses published between 2013 - 2021 that met the established inclusion criteria were included.Conclusion: diagnostic indicators of Autism Spectrum Disorder (ASD) in children are crucial for the family as a whole to lead a more age-appropriate life. ASD is increasingly common in society, but many are still unaware of the signs in their children, which delays detection and creates difficulties for everyone. Early intervention and appropriate support can significantly improve the prognosis of the disorder and help find the best treatment for the child

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Two-stage window screening and development trajectories in early identification of autism spectrum disorder among Han Chinese children

Cited by 3 publications

References 21 publications

Families with high-risk characteristics and diagnoses of attention-deficit/hyperactivity disorder, autism spectrum disorder, intellectual disability, and learning disability in children: A national birth cohort study

Families with high-risk characteristics and diagnoses of attention-deficit/hyperactivity disorder, autism spectrum disorder, intellectual disability, and learning disability in children: A national birth cohort study

Urban–Rural Disparity in the Incidence of Diagnosed Autism Spectrum Disorder in Taiwan: A 10-Year National Birth Cohort Follow-up Study

Characteristics for the diagnosis of Autism Spectrum Disorder

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