A petrological study was performed on an eclogite-vein system from the Dabie ultrahigh-pressure terrane by focusing on high-pressure (HP) fluid-rock interaction and mass transfer during exhumation. The veins comprise mainly garnet and quartz and resulted from a HP leaching process along fractures in the eclogite during exhumation. Relict peak garnet, phengite, and apatite in this rock system were altered by HP fluids forming characteristic compositional zonings. Zoned garnet in the eclogite records an isothermal exhumation from 3.3 GPa and 665-680°C. Partial dissolution of garnet and a back incorporation of Mn-heavy rare earth element (REE)-Y increased the content of these elements in the altered garnet zone in the veins. Altered phengite is characterized by a Ba-rich rim. Fluid-aided alteration reduced the light REE (LREE) contents and produced oriented monazite, calcite, and pyrrhotite inclusions within apatite, reflecting mobilization and redistribution of LREEs, CO 3 2− , Fe, and S between these minerals. The active HP fluid is proposed to have been a Si-Al-Na-Ba-rich aqueous fluid, as indicated by sodic plagioclase rims around various eclogitic minerals and by the altered phengite composition. Mass balance calculations reveal that LREEs, middle REEs, and Zr-Hf-Th-U were added to and Li, large ion lithophile elements, and Ti-Nb were removed from the quartz-garnet veins, requiring a high fluid flux. These findings shed new light on the nature and behavior of HP fluids and highlight their key role in resetting mineral chemistry and mass transfer in subduction zone metamorphic environments. . (2019). High-pressure fluid-rock interaction and mass transfer during exhumation of deeply subducted rocks: insights from an eclogite-vein system in the ultrahigh-pressure terrane of the Dabie The Dabie-Sulu orogenic belt in east-central China is considered to be one of the largest UHP terranes on Earth. This belt resulted from the Triassic continental collision between the North China and South China blocks (Ernst et al., 2007;Li et al., 1993;Zhang et al., 2009). It is separated into the eastern Sulu terrane and the western Dabie terrane by the sinistral Tanlu strike-slip fault. The western part of the Dabie terrane is further truncated by the Shangma fault and known as the Hongan terrane (Figure 1a).Several large-scale EW trending faults divide the Dabie terrane into five major lithotectonic units with different metamorphic histories (Hacker et al., 2000;Zheng et al., 2005). From north to south, these units are (1) the Beihuaiyang greenschist-facies unit made up of low-grade metasedimentary and metaigneous rocks that are overlain by Jurassic-Cretaceous sedimentary and volcanic rocks; (2) the North Dabie high-T granulite-facies unit composed of typical amphibolite-to granulite-facies rocks, migmatitic gneisses, and minor mafic to ultramafic rocks; (3) the Central Dabie medium-T/UHP eclogite-facies unit including abundant orthogneisses and paragneisses that enclose subordinate bodies of coesite-bearing eclogite, pure to imp...