Two wound-covering materials in the surgical treatment of oral submucous fibrosis: a clinical comparison

Pradhan, Harsha; Gupta, Hemant; Sinha, VP; Gupta, Sumit; Shashikanth, MC

doi:10.1016/s2212-4268(12)60004-9

Cited by 13 publications

(13 citation statements)

References 14 publications

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“…The results of medical and physical therapies for OSF management are shown in Table 3 [28][29][30][31][32][33][34][35] and those of representative surgical therapies are summarized in Table 4. [36][37][38][39][40]…”

Section: Tre Atmentmentioning

confidence: 99%

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Oral submucous fibrosis in Asian countries

Peng

Chen

et al. 2019

J Oral Pathology Medicine

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Oral submucous fibrosis (OSF) is a chronic, insidious, and progressive oral mucosal disease that affects entire oral cavity and sometimes pharynx. It is precancerous and characterized by blanching and burning sensation of oral mucosa, staining of teeth and gingiva, and restricted mouth opening. It is multifactorial with a high incidence in chewers of areca nut (AN). This oral potentially malignant disorder has a high rate of malignant transformation rate (7%-30%) to oral squamous cell carcinoma (OSCC). 1 It is prevalent in Asian countries and has spread in Europe and North America. The prevalence of OSF was reported to be 1.0%-3.03% in Hunan Province, mainland China, 2 0.15%-14.4% in Vietnam, 3 and 0.086%-17.6% in Taiwan. 4 In the past decades, many efforts have been devoted to etiology, pathogenesis, and treatment of OSF. However, the research progress is still unsatisfactory. For instance, the etiology of OSF is commonly attributed to AN chewing, but some OSF patients did not have the habit. Also, there is no staging or grading scheme universally accepted and employed by clinicians, pathologists, and surgeons. Moreover, the pathogenesis and mechanism of OSF transformation into carcinomas are still obscure. Undoubtedly, it is crucial to make further studies of OSF to fill in the gaps. This article, for the first time, provided a detailed review of research advances of OSF in Asian countries, based on a comprehensive literature search using several primary databases (Figure 1), in which the terminologies, for example, OSF and oral potential malignant diseases (OPMD), were used. The OSF's etiology, histopathology, pathogenesis, clinical manifestations, diagnosis and differential diagnosis, and treatments were reviewed. The main challenges and corresponding measures were also discussed for guiding clinical research and practice concerning the disease. | E TI O LO GYOral submucous fibrosis is characterized by its multifactorial etiology. The most commonly identified factors include AN chewing, nutritional disorders, and genetic predisposition. They act individually or synergistically in the development of OSF. AbstractOral submucous fibrosis (OSF) is a chronic, insidious, and progressive oral mucosal disease that affects entire oral cavity and sometimes pharynx. This oral potentially malignant disorder has a high rate of malignant transformation (7%-30%) to oral squamous cell carcinoma (OSCC), posing global problems for public health. Due to enormous efforts dedicated to this disease in the past decades, there have been significant advances in identification of its etiology and pathogenesis as well as development of corresponding therapeutic approaches, in spite of several challenges. This study reviewed the existing literature concerning OSF in Asian countries, encompassing its etiology, histopathology, pathogenesis, clinical manifestations, diagnosis and differential diagnosis, and treatments. For improving treatment of OSF, the multifactorial etiology analysis, incorporation of effective molecular pathways, cy...

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Section: Tre Atmentmentioning

confidence: 99%

“…For the disease at the intermediate or advanced stage, physical and/or surgical therapies are necessary for alleviating symptoms of pain of oral mucosa and for increasing mouth opening. The results of medical and physical therapies for OSF management are shown in Table and those of representative surgical therapies are summarized in Table …”

Section: Treatmentmentioning

confidence: 99%

Oral submucous fibrosis in Asian countries

Peng

Chen

et al. 2019

J Oral Pathology Medicine

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“…They found that the use of collagen membrane following excision of fibrotic bands in the management of oral submucous fibrosis, though statistically not significant gave better results with respect to post operative mouth opening as seen with a 6-month follow up. Pradhan et al [33] also in a similar study found a significant difference in the postoperative mouth opening, an insignificant difference for post surgical morbidity and higher grades of surgical convenience in using collagen sheet as a wound dressing material as compared to buccal pad of fat. Reddy et al [39] found good results in cases of OSMF when they impregnated dexamethasone in the collagen graft after excision of fibrous bands.…”

Section: Collagen For Coverage Of Soft Tissue Defects Of Oral Mucosa mentioning

confidence: 82%

“…[32] Other reconstructive options which have been used in the past include nasolabial flaps, transposition of the buccal pad of fat, dorsal tongue flap, radial forearm flaps, flaps of the temporalis fascia/muscle or both, palatal island flaps to cover surgical defects, each having their own advantages and shortcomings. [33,34] Use of island palatal flap has limitation such as its involvement with fibrosis and second molar tooth extraction is required for flap cover without tension. Bilateral palatal flaps leave a large raw area on palatal bones.…”

Section: Collagen For Coverage Of Soft Tissue Defects Of Oral Mucosa mentioning

confidence: 99%

Collagen membrane for reconstruction of soft tissue defects after surgery of oral cancer and precancer: a brief review

Vastani¹,

Chourasia²,

Pahlajani³

et al. 2016

PAR

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There are some surgeries after which a temporary cover for raw wounds is required to ensure healing. Some of those circumstances are loss of tissue due to burns, trauma, amputation, chronic ulcer, leprosy, and skin graft sites. Although the body initiates regeneration mechanisms, however the time taken for complete healing of wounds is unpredictable. Also, there is a tendency for long standing wounds to undergo infection and scarring. Oral mucosa is no exception to scarring and infection of wounds and there has always been a search for new materials that can be used for coverage of oral defects. Xenogenous collagen is one such grafting material. Over the years collagen implant solutions for a number of clinical applications include general surgery, burn surgery, neurosurgery, plastic and reconstructive surgery, oral surgery, and peripheral nerve and tendon surgery. This paper aims to focus on collagen as an effective option of wound closure in plastic and reconstructive surgery of the head and neck, especially after loss of soft tissue following resection of oral malignancies.

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“…13 Pradhan et al did a comparative study to evaluate buccal fat pad and collagen sheets for defect closure and concluded collagen sheet is superior in outcome compared to buccal fat pad. 14 Borle R on his 25 advanced OSMF case series did melolabial flap reconstruction along with coronoidectomy and concluded it being an effective reconstructive option though the concern being the presence of extra oral scars.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Melolabial Flap Reconstruction Post Fibrotomy: A Novel Alternative Option

2016

IJDA

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ABSTRACT:Melolabial flap previously known as nasolabial flap is a proven reconstructive option for correcting defects of the face preferably of the nose and forehead. Two subtypes based on different pedicles exists namely superiorly and inferiorly pedicled melolabial flap. Melolabial flap can also be successfully incorportated through the raised tunnel to correct various defects of the buccal mucosa. The present case report highlights the usefulness of the bilateral melolabial flap as an alternative method to reconstruct buccal mucosa defect of a oral submucous fibrosis case treated by fibrotomy.

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Two wound-covering materials in the surgical treatment of oral submucous fibrosis: a clinical comparison

Cited by 13 publications

References 14 publications

Oral submucous fibrosis in Asian countries

Oral submucous fibrosis in Asian countries

Collagen membrane for reconstruction of soft tissue defects after surgery of oral cancer and precancer: a brief review

Bilateral Melolabial Flap Reconstruction Post Fibrotomy: A Novel Alternative Option

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