2018
DOI: 10.20944/preprints201811.0109.v2
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Two-Year Data Comparison of Ab Interno Trabeculectomy and Trabecular Bypass Stenting Using Exact Matching

Abstract: Purpose: To create a highly balanced comparison of ab interno trabeculectomy (Trabectome, AIT) and trabecular bypass stenting (iStent, TBS).Setting: Eye and Ear Institute, Pittsburgh, Ross Eye Institute, Buffalo, and Glaucoma Associates of Texas, Dallas, USA.Design: Retrospective Exact Matching analysis.Methods: AIT and TBS patients were included from three large glaucoma practices. The primary outcome measure was the unmedicated IOP ≤ 21 mmHg at 2-year follow-up visit. A secondary measure was unmedicat… Show more

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Cited by 5 publications
(17 citation statements)
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“…In T, medications continued to decline throughout the study. Our experience with the IS2 resembled the IS1 [3] except that IS1 patients had an IOP increase above baseline that was higher (about 15%) despite counteracting this trend by using approximately 30% more glaucoma medications compared to the companion T eyes.…”
Section: Discussionmentioning
confidence: 72%
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“…In T, medications continued to decline throughout the study. Our experience with the IS2 resembled the IS1 [3] except that IS1 patients had an IOP increase above baseline that was higher (about 15%) despite counteracting this trend by using approximately 30% more glaucoma medications compared to the companion T eyes.…”
Section: Discussionmentioning
confidence: 72%
“…Such microincisional glaucoma surgeries (MIGS) are now often performed as primary glaucoma surgeries instead of more extensive, traditional procedures (trabeculectomy, tube shunt) because of a low complication rate [4] , short procedure time and ability to combine them with outpatient cataract surgery. In eyes with stents, we found evidence of declining function in the form of increasing IOP and glaucoma medications above preoperative levels while IOP and medications reduced in matched eyes that had undergone TM ablation [3] . In the present study, we examined whether a smaller, second-generation trabecular bypass stent (IS2, iStent inject, Glaukos Corp., San Clemente, CA) would be affected differently.…”
Section: Introductionmentioning
confidence: 75%
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“…In general, the mean 1-year IOP after MIGS procedures ranges between 12 and 16 mm Hg, which is higher than the episcleral venous pressure. [9][10][11][12][13][14][15] This raised the question why MIGS procedures that target SC are unable to lower IOP to episcleral venous pressure levels.…”
Section: Introductionmentioning
confidence: 99%