“…Remarkably, however, the teeth in these cases were stored in a moist environment to preserve the viability of the PDL cells [3,7,8,[11][12][13]18,19,90], suggesting that extra-alveolar stay time should be considered in the context of tooth conservation approaches. In this context, it has been previously suggested [8,10,91] that preservation of the tooth in an extra-oral humid environment, such as water, saline, and saliva, may positively influence the results of IR, making the procedure more predictable and thus supporting the hypothesis that the periodic submersion of the tooth in a bath of Hank's balanced salt solution during the root resection phase may be the best approach to avoid root desiccation [91].…”