2008
DOI: 10.1016/j.jad.2007.10.017
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Two-year prospective study of major depressive disorder in HIV-infected men

Abstract: Objective-The risks and factors contributing to major depressive episodes in HIV infection remain unclear. This 2-year prospective study compared cumulative rates and predictors of a major depressive episode in HIV-infected (HIV+) men (N=297) and uninfected (HIV−) risk-group controls (N=90).Method-By design participants at entry were without current major depression, substance dependence or major anxiety disorder. Standardized neuromedical, neuropsychological, neuroimaging, life events, and psychiatric assessm… Show more

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Cited by 97 publications
(88 citation statements)
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“…Cognitive slowing may be a result of the disease process or may be secondary to depression. Another consequence may be HIV-associated dementia, with accompanying characteristics of irritability, aggression or psychosis (Atkinson, 2008).…”
Section: Hiv/aids and Mental Illnessmentioning
confidence: 99%
See 1 more Smart Citation
“…Cognitive slowing may be a result of the disease process or may be secondary to depression. Another consequence may be HIV-associated dementia, with accompanying characteristics of irritability, aggression or psychosis (Atkinson, 2008).…”
Section: Hiv/aids and Mental Illnessmentioning
confidence: 99%
“…Individually, these factors have profound mental-health ramifications, but, collectively, they serve as barriers to effective interventions. Consequently, clinicians and program planners must recognize that HIV/AIDS can severely impact an individual's health and mental-health status (UNAIDS, 2008) and that psychiatric disorders and symptoms are very common among at-risk and HIV-infected individuals (Harris, 1995;Atkinson et al, 2008).…”
Section: Introductionmentioning
confidence: 99%
“…Some studies have noted that the rate of mental illness is elevated among individuals who are HIV positive. For example, Atkinson, Heaton, Patterson, et al [7] found that patients who experience HIV-related symptoms are more likely to have a major depressive episode compared to individuals who are asymptomatic or are not infected with HIV. Pence, Miller, Whetten, Eron, and Gaynes [8] found that 39% of HIV positive clinic patients had a mood or anxiety disorder, 21% had a substance use disorder, and 8% had both a mood/anxiety and a substance use disorder.…”
Section: Hiv Prevalence Among Individuals With a Severe Mental Illnessmentioning
confidence: 99%
“…In both the pre and post HAART era, depression as well as other disorders of anxiety and dysthymia are common. [6][7][8] Despite the high prevalence of depression and depressive symptoms among HIV-infected persons, these conditions remain under-diagnosed. 9,10 For these individuals, the consequences of unrecognized and untreated depression can be significant and include increased mortality, diminished quality of life, and impaired adherence to antiretroviral therapy.…”
mentioning
confidence: 99%