Two-Year Results of Translating the Diabetes Prevention Program Into an Urban, Underserved Community

Piatt, Gretchen; Seidel, Miriam; Chen, Hsiang Yu; Powell, Robert; Zgibor, Janice C.

doi:10.1177/0145721712458834

Cited by 29 publications

(28 citation statements)

References 21 publications

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“…With the physiologic benefits of type 2 diabetes and cardiovascular disease risk reduction through lifestyle change well-established in clinical [12,55] and translational settings [19,56,21,57,58], these findings help strengthen the case for increasing the use of HRQoL assessment tools in community lifestyle interventions. Building on these results, future studies should include measurement of HRQoL and explore relationships between HRQoL and specific clinical and behavioral outcomes in translational diabetes prevention programs.…”

Section: Resultsmentioning

confidence: 84%

Impact of a community-based lifestyle intervention program on health-related quality of life

et al. 2016

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Background The presence of risk factors for type 2 diabetes and cardiovascular disease, or the conditions themselves, contributes to lower health-related quality of life (HRQoL) among adults. Although community-based lifestyle intervention programs have been shown to be effective for improving risk factors for these diseases, the impact of these interventions on HRQoL has rarely been described. Purpose To examine changes in HRQoL following participation in the Group Lifestyle Balance program, a community translation of the Diabetes Prevention Program lifestyle intervention for adults with pre-diabetes and/or the metabolic syndrome. Methods Participants enrolled in the 12-month, 22-session intervention program (N=223) completed the EuroQol Health Questionnaire (EQ-5D-3L) at baseline, 6, and 12 months. Linear mixed effects regression models determined change in EQ-5D-Visual Analog Scale (VAS) and Index scores post-intervention. Results Mean EQ-5D-VAS improved by +7.38 (SE=1.03) at 6 months and by +6.73 (SE=1.06) at 12 months post-intervention (both; p<0.0001). Mean changes in EQ-5D Index values were +0.00 (SE=0.01; NS) and +0.01 (SE=0.01; p<0.05), respectively. Adjusted for age, baseline score, and achieving intervention goals, mean change in EQ-5D-VAS was +11.83 (SE=1.61) at 6 months and +11.23 (SE=1.54) at 12 months (both; p<0.0001). Adjusted mean change in EQ-5D Index value was +0.04 (SE=0.01) at 6 months and +0.05 (SE=0.01) at 12 months (both; p<0.01). Conclusions Participation in a community lifestyle intervention program resulted in improved HRQoL among adults with pre-diabetes and/or the metabolic syndrome. These benefits to HRQoL, together with improved clinical and behavioral outcomes, should increase the appeal of such programs for improving health.

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Section: Resultsmentioning

confidence: 84%

Impact of a community-based lifestyle intervention program on health-related quality of life

et al. 2016

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“…The DPP-GLB program, delivered by DPSC trained prevention professionals in face to face groups and/or via DVD, has been shown to be effective in reducing weight and other risk factors for diabetes and CVD in several community settings (24, 25, 27-29, 32, 33, 35, 37), but has not been evaluated within a workplace setting.…”

Section: Methodsmentioning

confidence: 99%

Improving Employee Health

Kramer

Molenaar

Arena

et al. 2015

Journal of Occupational &Amp; Environmental Medicine

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Objective To determine if an evidence-based, behavioral lifestyle intervention program delivered at a worksite setting is effective in improving type 2 diabetes and CVD risk factors. Methods A randomized six-month delayed control design was utilized, with two-thirds of the participants assigned to begin intervention immediately and one-third beginning six months later. The year-long program (weekly for 3 months transitioning to monthly) focused on weight loss and increasing physical activity. Results The immediate intervention group had greater mean weight loss (−10.4 lbs., 5.1%, vs. −2.3 lbs., 1%, p=0.0001) than the delayed control group at 6 months and relatively greater improvements in activity, HbA1c and other risk factors. The delayed group experienced similar improvements after completing the intervention program. Conclusions A worksite behavioral lifestyle intervention is feasible and effective in significantly improving risk factors for diabetes and CVD.

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“…Also, of those who lost at least 5% of their body weight post-intervention, 52.6% maintained it at 24 months, weighing approximately 20 lbs. less than at baseline [7].…”

Section: Introductionmentioning

confidence: 69%

“…A recent meta-analysis showed that weight loss with the GLB was 3.99% at post-intervention compared to 7% with the DPP [6]. One of the few GLB intervention studies that provide longer term weight loss maintenance data found that the probability of achieving a 5% weight loss at 3 months was 45.7% (why the results were reported as probabilities and not actual percentages of weight loss is unclear), but only 17.3% of participants maintained this weight loss 1 year post-intervention [7]. Also, of those who lost at least 5% of their body weight post-intervention, 52.6% maintained it at 24 months, weighing approximately 20 lbs.…”

Section: Introductionmentioning

confidence: 99%

The effects of if-then plans on weight loss: results of the 24-month follow-up of the McGill CHIP Healthy Weight Program randomized controlled trial

Knaüper

Shireen

Carrière

et al. 2020

Trials

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Background: Current evidence suggests that some of the most effective weight loss approaches are changes in dietary and physical activity behaviors through lifestyle modification programs. The Group Lifestyle Balance (GLB) program is a group-based behavior modification program aimed at changing diet and physical activity for weight loss. It was developed to be more cost-effective and easier to disseminate than its individually administered parent program, the Diabetes Prevention Program (DPP). However, the average weight loss following participation in the GLB is only approximately 3.5%, with low long-term weight loss maintenance. Purpose: We aimed to optimize the weight loss outcomes of the GLB to increase the efficacy already afforded by its cost-effectiveness and ease of dissemination. We did this by integrating the habit formation tool of if-then plans into the program. This program is called the enriched GLB or the McGill Comprehensive Health Improvement (CHIP) Healthy Weight Program. Results at 3 and 12 months of participation have already been published elsewhere. They showed no between-group differences between the standard and enriched GLB but higher weight loss in both groups compared to the DPP. This paper reports the long-term weight loss maintenance data following participation in the program. Methods: Of the 172 participants enrolled at the beginning of the study, data from 110 participants were available and analyzed at 24 months, i.e., 12 months after the end of the 12-month intervention. Results: No between-group difference in weight loss maintenance was observed. Pooled results showed a significant weight regain from 12 to 24 months, i.e., an average of 7.85 lbs. of the 20.36 lbs. lost. However, participants from both groups were still 12.51lbs or 6.13% lighter at 24 months than at baseline. Conclusion: If-then plans did not result in a higher percentage of weight loss at 24-month follow-up compared to the standard GLB. However, at 24 months, both groups did show a maintenance of a significant portion of the weight lost at the end of intervention. Trial registration: ClinicalTrials.gov Identifier: NCT02008435, registered 6 December 2013.

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Two-Year Results of Translating the Diabetes Prevention Program Into an Urban, Underserved Community

Abstract: Risk reduction and weight loss maintenance are possible following a GLB intervention and have substantial potential for future public health impact.

Cited by 29 publications

References 21 publications

Impact of a community-based lifestyle intervention program on health-related quality of life

Impact of a community-based lifestyle intervention program on health-related quality of life

Improving Employee Health

The effects of if-then plans on weight loss: results of the 24-month follow-up of the McGill CHIP Healthy Weight Program randomized controlled trial

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