Two years of continued early treatment for recent‐onset schizophrenia: a randomised controlled study

Gråwe, Rolf W.; Falloon, Ian R. H.; Widen, Jan H.; Skogvoll, Eirik

doi:10.1111/j.1600-0447.2006.00799.x

Cited by 115 publications

(125 citation statements)

References 44 publications

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“…These findings could reflect a strong motivation and inspiration of those family caregivers in the SPBB towards better patient care and outcomes in the community-based rehabilitation and mental healthcare service, as suggested by other family intervention studies in first-episode psychosis (Grawe et al, 2006, Petrakis et al, 2013. In line with the symptom reduction, the patients' risk and 27 frequency of re-hospitalisations in the SPBB participants were also significantly reduced (i.e., 64% and 59% reduction, respectively, at 6 months post-intervention).…”

Section: Discussionmentioning

confidence: 99%

“…Self-directed, problem-solving strategies have been increasingly used or integrated into interventional studies as part of the psychosocial skills training for family caregivers or patients in an early stage of serious mental disorders, for example, schizophrenia, substance misuse and other psychotic disorders (Grawe et al, 2006, Gylnn et al, 2006, Dixon et al, 2011. Nevertheless, the effectiveness of self-help problem-solving approach to family intervention in recent-onset psychosis, or inclusion of this bibliotherapy programme, in community mental health care has not yet been studied; and thus their contributions to these families' health outcomes are uncertain (Onwumere et al, 2011).…”

Section: Discussionmentioning

confidence: 99%

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The effectiveness of manual-guided, problem-solving-based self-learning programme for family caregivers of people with recent-onset psychosis: A randomised controlled trial with 6-month follow-up

Chien

Yip

Liu

et al. 2016

International Journal of Nursing Studies

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What is already known about the topic Recent-onset psychosis is a distressing and disabling mental disorder for both young patients themselves and their first-time family caregivers. A few approaches to family intervention in psychosis such as psycho-education have resulted in a few positive patient outcomes, mainly mental state and relapse from illness, but comparatively few caregivers' health outcomes. Self-care, coping and problem-solving skills training, which is based on the stressvulnerability and stress-coping model, have been more frequently adopted in patients 3 with chronic illnesses, as well as their family carers. Nevertheless, more research should be conducted to prove its positive effects as an early intervention for people with recent-onset psychosis. What this paper adds Self-help, problem-solving-based manual-guided learning programme, or bibliotherapy (in addition to usual care), is more effective to improve family caregivers' and patients psychosocial health conditions in recent-onset psychosis over 6-month follow-up, when compared to usual family support services only. Methods:Following pre-test measurement, caregivers were assigned randomly to one of two study groups: a 5-month self-help, problem-solving-based manual-guided self-learning (or bibliotherapy) programme (in addition to usual care), or usual family support service only.Varieties of patient and caregiver health outcomes were assessed and compared at baseline and at 1-week and 6-month post-intervention. Results:One hundred and eleven (96%) caregivers completed the 6-month follow-up (two post-tests); 55 of them (95%) completed ≥4 modules and attended ≥2 review sessions (i.e., 75% of the intervention). The family participants' mean age was about 38 years and over 64% of them were female and patient's parent or spouse. Multivariate analyses of variance indicated that the manual-guided self-learning group reported significantly greater improvements than the usual care group in family burden [F(1,110) Conclusions: Problem-solving-based, manual-guided self-learning programme for family caregivers of adults with recent-onset psychosis can be an effective self-help programme and provide medium-term benefits to patients' and caregivers' mental health and duration of patients' re-hospitalisations.Keywords: bibliotherapy, family intervention, problem-solving, randomised controlled trial, recent-onset psychosis, self-learning. 6What is already known about the topic  Recent-onset psychosis is a distressing and disabling mental disorder for both young patients themselves and their first-time family caregivers. A few approaches to family intervention in psychosis such as psycho-education have resulted in a few positive patient outcomes, mainly mental state and relapse from illness, but comparatively few caregivers' health outcomes. Self-care, coping and problem-solving skills training, which is based on the stressvulnerability and stress-coping model, have been more frequently adopted in patients with chronic illnesses, as well as their f...

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

The effectiveness of manual-guided, problem-solving-based self-learning programme for family caregivers of people with recent-onset psychosis: A randomised controlled trial with 6-month follow-up

Chien

Yip

Liu

et al. 2016

International Journal of Nursing Studies

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“…W 2010 r. Bird i wsp. opublikowali wyniki metaanalizy kilku dużych kontrolowanych badań na temat wczesnych interwencji w różnych ośrodkach na świecie -badania: COAST [93], LEO [94], OPUS [95], OTP [96], w której wykazali, że w okresie pierwszych pięciu lat trwania choroby takie wczesne i szerokie interwencje mają przewagę nad opieką standardową. Na podstawie wyników tej metaanalizy uważa się, że wczesna, kompleksowa interwencja u osób chorych na schizofrenię skutkuje istotną klinicznie redukcją ryzyka nawrotu choroby i ponownych hospitalizacji.…”

Section: Implikacje Terapeutyczneunclassified

“…The idea of early intervention programs for schizophrenic patients includes not only early detection of disorders, but also multidisciplinary, com-prehensive care for patients and their families in the form of specialized pharmacological and non-pharmacological therapy: family interventions, behavioral cognitive therapy, social skills training, and problem solving, help with getting a job and extensive psycho-educational interventions for patients and their families. In 2010, Bird et al published a meta-analysis of several large controlled studies of early intervention in different centers around the world -COAST [93], LEO [94], OPUS [95], OTP [96], in which they demonstrated that during the first five years of illness, such early and widespread interventions have the advantage over standard care. Based on the results of this meta-analysis, early intervention in schizophrenic patients is believed to result in a clinically significant reduction in the risk of relapse and re-hospitalization.…”

Section: Therapeutic Implicationsmentioning

confidence: 99%

Review paper. Neuropsychological dimension of schizophrenia - evaluation possibilities and therapeutic implications

Makarewicz

Karakuła-Juchnowicz

Łobejko

2017

Current Problems of Psychiatry

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Introduction: In the last decades, researchers' attention has been focused on cognitive dysfunction in schizophrenia. Numerous studies indicate the existence of neurodegenerative deficits in schizophrenia including, but not limited to, motor functions, learning and memory, executive functions, attention, language, spatial skills and general intelligence.Method: A review of available literature on the topic of the past two decades, available in the Pubmed, EBSCO, SCOPUS databases has been made using the keywords: schizophrenia, cognition, early intervention.Results: Cognitive dysfunction is an important feature of the prodromal phase and the first episode of schizophrenia. Researchers have thus proposed to initiate early therapeutic interventions for people with so-called risky mental conditions. The article includes the reference to research on neurocognitive disorders essence in schizophrenia, the definition and review of methods used to identify specific cognitive deficits and issues related to risk of developing psychosis and early therapeutic intervention in high-risk states.Conclusions: Researchers report the importance of detecting cognitive disorders in the early stages of schizophrenia. This broadens the range of therapeutic interventions and enables early intervention in the increased risk of psychosis.

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“…The focus of many prior studies, however, is on interventions for groups other than adolescents, including adults with schizophrenia (Barrowclough et al, 2001;Dyck, Hendryx, Short, Voss, & McFarlane, 2002;Dyck et al, 2000;Farooq et al, 2011;Li & Arthur, 2005), first episode psychosis (Agius, Shah, Ramkisson, Murphy, & Zaman, 2007;Breitborde et al, 2011), or recent-onset schizophrenia (Grawe, Falloon, Widen, & Skogvoll, 2006;Lenior, Dingemans, Linszen, de Haan, & Schene, 2001;Lenior, Dingemans, Schene, Hart, & Linszen, 2002). Studies of siblings of adolescents with schizophrenia also have been limited (Friedrich, Lively, & Rubenstein, 2008).…”

mentioning

confidence: 99%

Lessons Learned From Research With Adolescents With Schizophrenia and Their Families

Lee

Schepp

2013

Archives of Psychiatric Nursing

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The purpose of this study is to present our experiences of conducting a randomized clinical trial of a self-management intervention for adolescents with schizophrenia and their families. Challenges and strategies of recruiting subjects; engaging families in self-management intervention; tailoring interventions for this population were discussed. Participants' comments on their experience were presented. Adolescents and their families are poorly prepared to manage schizophrenia; therefore psychosocial interventions should address their needs. Impaired cognitive functioning in adolescents with schizophrenia should be a target for interventions and should be considered in planning interventions.

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Two years of continued early treatment for recent‐onset schizophrenia: a randomised controlled study

Abstract: Evidence-based treatment achieves greater clinical benefits than pharmacotherapy and case management alone for recent-onset schizophrenia.

Cited by 115 publications

References 44 publications

The effectiveness of manual-guided, problem-solving-based self-learning programme for family caregivers of people with recent-onset psychosis: A randomised controlled trial with 6-month follow-up

The effectiveness of manual-guided, problem-solving-based self-learning programme for family caregivers of people with recent-onset psychosis: A randomised controlled trial with 6-month follow-up

Review paper. Neuropsychological dimension of schizophrenia - evaluation possibilities and therapeutic implications

Lessons Learned From Research With Adolescents With Schizophrenia and Their Families

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