Type 1 Diabetes and Autism: Is there a link?

Comparing Health Status, Health Trajectories and Use of Health and Social Services between Children with and without Developmental Disabilities: A Population‐based Longitudinal Study in Manitoba

“…). Our finding, however, contrasts with the findings of some other studies which reported no increased risk of diabetes in children with ASDs (Harjustsalo & Tuomilehto, ) or intellectual disabilities (Oeseburg, ). Our analysis also showed that over time, the proportion of children with DDs who had a diagnosis of diabetes increased significantly.…”

“…Of those that examined disparities in physical health conditions or utilization of health and social services, the majority were cross-sectional, using data from small and non-representative samples of populations, and reporting inconsistent results. For example, a study of the prevalence of diabetes in 5,178 children under 15 years of age with autism spectrum disorders (ASDs) in Finland (Harjutsalo & Tuomilehto, 2006), using the Prospective Childhood Diabetes Registry of Finland, found no increased risk of diabetes in children with ASDs compared to the children in the general population. In a study of adolescents aged 12-18 years who had ASDs and Down syndrome (DS) (Rimmer et al 2010), those with autism were two to three times more likely to be obese than those in the general population, while adolescents with other types of intellectual disabilities were less likely to be overweight or obese.…”

Type 1 Diabetes and Autism Association Seems to Be Linked to the Incidence of Diabetes

“…A lthough there is a strong association between lower-extremity amputation (LEA) and HbA 1c (A1C) in diabetic patients (1,2), little information is available on glucose control in the period preceding and following LEA (3). Our objective was to evaluate the predictors of LEA and to examine the role of blood glucose control during the year before and the year after admission.…”

T. gondii Infection Acquired during Pregnancy and/or after Birth may be Responsible for Development of both Type 1 and 2 Diabetes Mellitus

“…In mothers of patients with autism, Comi et al [822] reported higher incidence of autoimmune diseases compared with controls, and specifically autoantibodies implicated in autoimmune thyroid disorders also have been found with an increased prevalence in the patients with T1DM [823][824][825]. Although the studies performed by Harjutsalo & Tuomilehto [826] in northern Finland did not support their suggestion about the link between T1DM and ASD, Iafusco et al [827] in their cohort of patients a Median inhibitory dose, a measure of tachyzoite inhibition; b Median toxicity dose,a measure of cytotoxicity;…”