Type 2-diabetes og metabolsk syndrom før og etter gastrisk bypass

Effect of the definition of type II diabetes remission in the evaluation of bariatric surgery for metabolic disorders

“…At a median follow‐up of 23 months after surgery, rates of complete remission of type II diabetes were 40·6 per cent after gastric bypass, 26 per cent after sleeve gastrectomy and 7 per cent after gastric banding. These rates are substantially lower than previously reported remission rates of approximately 83 per cent for gastric bypass, 81 per cent for sleeve gastrectomy and 44 per cent for gastric banding2–8. Markers of glycaemic control such as HbA1c were no different between the groups, but there was a difference in additional hypoglycaemic agents used.…”

“…Data were collected prospectively in three bariatric surgery centres, two in the UK and one in Norway4. For the UK centres, data were also collected from the National Bariatric Surgery Registry, the result of a collaboration between the Association of Laparoscopic Surgeons of Great Britain and Ireland, Association of Upper Gastrointestinal Surgery and British Obesity and Metabolic Surgery Society.…”

Can a Protocol for Glycaemic Control Improve Type 2 Diabetes Outcomes After Gastric Bypass?

“…These observations are more in line with previous reports [5,18,19], whilst the complete remission rates based on the ADA consensus statement are consistent with recent studies referring to the same criteria [21].…”

“…This probably reflects the more stringent criteria used for complete diabetes remission in our study [15] compared to those previously used [1,5,18,19]. It cannot be excluded that a longer duration or an increased severity of T2DM among participants of our study may have negatively affected the remission rate [20].…”

“…Applying the previously used criteria of diabetes remission [5,18,19] to our study population, 41 patients (82.0%) in the protocol-driven group and 17 patients (34.7%) in the non-protocol-driven group achieved remission from diabetes at 1 year after surgery ( Table 2). These observations are more in line with previous reports [5,18,19], whilst the complete remission rates based on the ADA consensus statement are consistent with recent studies referring to the same criteria [21].…”