Medicinal chemistry and pharmacological efforts to develop drugs is a complicated process due to drug screening convention limitation. As a result, herbal medicine tradition must be introduced. Methods General scenario of herbal medicine Herbal medicine has a long history of evolution in styles and practice worldwide. In its early stage, herbal or animal medicines were widely utilized over many different countries, including Greece, as allopathic medicine, Ayurvedic medicine in India and traditional Chinese medicine. 3-7 Yet, most of such countries lost this tradition. China still maintains herbal medicine in modern day because it reserves many ancient medical books by leading publication systems in the ancient world. China has a long reputation of treating a wide variety of diseases by herbal medicine. This type of medical practice dates back at least 2000 years. Several earliest medical books were published between 100BC to 1900AD. It has been successfully managed for large endemics since the era of Zhong-Jin Zhang (AD150-219) in China. According to theory of traditional Chinese medicine (TCM), human diseases can be categorized with patient's imbalance between "Yin-Yang". TCM doctors try to combat these patterns of symptoms (like fever, cough and immune deficiency) by strengthening, modulating and offsetting these damaged "Yin-Yang" in human bodies by formulated herbals. 8-11 The formulated herbal medicines contain large components of chemical admixtures and somewhat like modern drug combinations in western styles of therapeutic philosophy. TCM for various diseases TCM has its advantageous and disadvantageous to manage diseases. The advantages for TCM can be both acute disease (like microbial or viral infection) and chronic diseases (like cancer, diabetes, obesity, bone diseases and metabolic symptoms). 12-24 Apart from different disease types, some disease symptoms are also within the range of TCM. For example, Ma-Xing-Shi-Gan-Tang is prescribed to remove toxic heat obstruction in the lungs of infected patients. These items of herbal formulas are historically used as the preventive measures to attack widespread epidemics like avian flu or Ebola epidemics in modern days. 25-31