Type A behavior pattern and hyperthymic temperament: Possible association with bipolar IV disorder

Wang, Yumei; Terao, Takeshi; Hoaki, Nobuhiko; Goto, Shinjiro; Tsuchiyama, Kounosuke; Iwata, Noboru; Yoshimura, Reiji; Nakamura, Jun

doi:10.1016/j.jad.2011.04.017

Cited by 20 publications

(16 citation statements)

References 26 publications

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“…According to the DCPR, patients with cardiac conditions who presented type A (up to one third of the population) tended to display minimization of psychological impact and possible life-threatening consequences of cardiac disease [74]. This finding is in line with previous studies documenting an overlap between type A behavior and both hypomania and hyperthymic temperament, which are subclinical manifestations of the bipolar spectrum [75,76,77]. Such association could explain both an increased cardiac risk in patients with bipolar disorders [78,79] and a lack of improvement in cardiac prognosis after the treatment of depression.…”

Section: Type a Behavior: A Reassessment Is Overduesupporting

confidence: 64%

Is Depression the Wrong Treatment Target for Improving Outcome in Coronary Artery Disease?

Rafanelli¹,

Sirri

Grandi³

et al. 2013

Psychother Psychosom

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Section: Type a Behavior: A Reassessment Is Overduesupporting

confidence: 64%

Is Depression the Wrong Treatment Target for Improving Outcome in Coronary Artery Disease?

Rafanelli¹,

Sirri

Grandi³

et al. 2013

Psychother Psychosom

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“…In other words, individuals with hyperthymic temperament may have a tendency towards Type A Behavioural Pattern (TABP), and TABP persons – like hyperthymics – may have short sleep time and short snooze time [41]. …”

Section: Similarities and Differences Between Essential Hypertensimentioning

confidence: 99%

Is Mania the Hypertension of the Mood? Discussion of A Hypothesis

Rihmer

Gonda²,

Döme³

2017

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Beyond both being biphasic/bidirectional disorders (hypo)mania and essential hypertension share a surprising number of similarities and an overlap between their genetics, biological background, underlying personality and temperamental factors, precipitating factors, comorbidity and response to treatment, indicating a possibly partially shared biological background. Based on theoretical knowledge, similarities related to characteristics, manifestation and course, and the results of pharmacological studies related to the effects and side effects of pharmacotherapies used in the treatment of these two distinct disorders, the authors outline a hypothesis discussing the similar origins of these two phenomena and thus mania being the hypertension of mood in memory of Athanasios Koukopoulos, one of the greatest researchers and theoreticists of mania of all time.

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“…Thirtyfive studies, comprising a total of 2238 bipolar disorder patients and 1560 healthy control subjects, were eligible for review and included in the meta-analysis with a minimum of one pair-wise comparison each. [11][12][13][19][20][21]26, Exclusion of full 63 text articles and reports were based on (a) data on BDNF levels were unavailable, [66][67][68] (b) patients not suffering from bipolar disorder, [69][70][71][72][73][74][75][76][77][78][79][80][81][82][83][84] (c) the study not evaluating peripheral BDNF levels, (d) the study being a review or a comment, [107][108][109][110][111][112][113][114][115][116][117][118][119] (e) the study not comparing states or comparing bipolar patients with healthy control subjects [120][121][122] and/or (f) the study investigated treatment of experimental nature 123,124 and (g) the study presenting duplicate data presented in an included article. …”

Section: Study Selectionmentioning

confidence: 99%

Peripheral blood brain-derived neurotrophic factor in bipolar disorder: a comprehensive systematic review and meta-analysis

2015

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Peripheral blood brain-derived neurotrophic factor (BDNF) has been proposed as a potential biomarker related to disease activity and neuroprogression in bipolar disorder, speculated to mirror alterations in brain expression of BDNF. The research area is rapidly evolving; however, recent investigations have yielded conflicting results with substantial variation in outcomes, highlighting the need to critically assess the state of current evidence. The aims of the study were to investigate differences in peripheral blood BDNF concentrations between bipolar disorder patients and healthy control subjects and between affective states in bipolar disorder patients, including assessment of the effect of treatment of acute episodes on BDNF levels. A systematic review of English language studies without considering publication status was conducted in PubMed (January 1950-November 2014), Embase (1974-November 2014) and PsycINFO (1806-November 2014), and 35 studies comprising a total of 3798 participants were included in the meta-analysis. The results indicated that crude peripheral blood BDNF levels may be lower in bipolar disorder patients overall (Hedges' g=-0.28, 95% CI: -0.51 to -0.04, P=0.02) and in serum of manic (g=-0.77, 95% CI: -1.36 to -0.18, P=0.01) and depressed (g=-0.87, 95% CI: -1.42 to -0.32, P=0.002) bipolar disorder patients compared with healthy control subjects. No differences in peripheral BDNF levels were observed between affective states overall. Longer illness duration was associated with higher BDNF levels in bipolar disorder patients. Relatively low study quality, substantial unexplained between-study heterogeneity, potential bias in individual studies and indications of publication bias, was observed and studies were overall underpowered. It could thus not be excluded that identified differences between groups were due to factors not related to bipolar disorder. In conclusion, limitations in the evidence base prompt tempered conclusions regarding the role of peripheral BDNF as a biomarker in bipolar disorder and substantially improving the quality of further research is warranted.

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Type A behavior pattern and hyperthymic temperament: Possible association with bipolar IV disorder

Cited by 20 publications

References 26 publications

Is Depression the Wrong Treatment Target for Improving Outcome in Coronary Artery Disease?

Is Depression the Wrong Treatment Target for Improving Outcome in Coronary Artery Disease?

Is Mania the Hypertension of the Mood? Discussion of A Hypothesis

Peripheral blood brain-derived neurotrophic factor in bipolar disorder: a comprehensive systematic review and meta-analysis

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