Type II pleuropulmonary blastoma mistaken for rhabdomyosarcoma: A case report

A, Karray; Boussetta, Abir; Sassi, Farah; Cherifi, Walid; Haouet, Slim; Gargah, Tahar

doi:10.1016/j.ijscr.2023.108261

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…As the patient's condition remained unclear, she underwent several medical investigations, including thoracic X-ray and spirometry, as well as consultation of an otorhinolaryngologist which did not reveal any pathology. Nevertheless, these investigations were important to rule out inflammatory [14][15][16][17] and neoplastic [18][19][20] lung diseases; albeit such conditions (e.g., tuberculosis, hypersensitivity pneumonitis, sarcoidosis, pleuropulmonary blastoma) are rare in children, they still have to be considered in the differential diagnosis. Normal spirometry findings were helpful to further exclude bronchial asthma.…”

Section: Discussionmentioning

confidence: 99%

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Grinevica,

Udre,

Balodis

et al. 2024

Brain Sciences

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Chronic cough in children and adolescents can be troublesome both to the patient and the whole family. The most common causes of chronic cough in children are protracted bacterial bronchitis and bronchial asthma. However, differential diagnostic workup and treatment can become complicated when a cough of different etiology is encountered, especially in a child having a complex medical history for an unrelated pathology. A cough lacking any identified somatic cause and response to medical treatment in combination with core clinical features of tics that include suppressibility, distractibility, suggestibility, variability, and the presence of a premonitory sensation is labeled tic cough. Here we discuss a case of an adolescent who had atrophy of the corpus callosum and a history of ventriculoperitoneal shunting due to hydrocephalus caused by stenosis of the sylvian aqueduct, but now presented with a debilitating dry cough lasting for several months. After physical causes of cough were ruled out, the diagnosis of tic cough was reached, and multidisciplinary treatment ensured complete recovery. To the best of our knowledge, this is the first reported case showing coincidence of tic cough and hydrocephalus. The co-occurrence of non-syndromic corpus callosum atrophy and tic cough might hypothetically suggest a predisposing pathogenetic link via reduced signaling through cortical inhibitory neurons; further studies are needed. The importance of careful assessment of medical history, clinical picture, and features of the cough itself are emphasized in order to reach the correct diagnosis. Increased awareness of medical society is mandatory to recognize tic cough and to distinguish it from the neurologic manifestations of organic brain pathology.

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Section: Discussionmentioning

confidence: 99%

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Grinevica,

Udre,

Balodis

et al. 2024

Brain Sciences

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Type II Pleuropulmonary Blastoma in a Two-Year-Old Girl: A Case Report and Literature Review

Ortega,

Ruano,

Ajebli

et al. 2024

Cureus

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Pleuropulmonary blastoma (PPB) is an extremely rare and highly malignant intrathoracic tumor in children, representing a unique form of aggressive primary lung carcinoma with a strong tendency for local recurrence. In this case report, we present a two-year-old girl who has had recurrent respiratory infections since birth. A chest X-ray revealed an abnormality, prompting a referral to a surgical team, where the lesion was identified as type II PPB based on histological analysis. After completing polychemotherapy, the patient was monitored for five years, during which clinical exams and imaging showed no evidence of disease. Diagnosing PPB requires a high index of suspicion due to its aggressive yet subtle presentation, as imaging findings and clinical symptoms may be nonspecific. This report emphasizes the diagnostic and management challenges of type II PPB, underscoring the importance of a multidisciplinary approach in low-resource settings. We explore potential prognostic factors, discuss treatment options, and propose individualized therapeutic strategies.

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Type II pleuropulmonary blastoma mistaken for rhabdomyosarcoma: A case report

Cited by 2 publications

References 18 publications

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Tic Cough in an Adolescent with Organic Brain Pathology—A Case Report and Literature Review

Type II Pleuropulmonary Blastoma in a Two-Year-Old Girl: A Case Report and Literature Review

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