Type V aplasia cutis congenita in a preterm newborn successfully resolved

Díaz, Esmeralda Silva; Menchón, María O Molini; Corrales, Andrea Estébanez; García‐Vázquez, Alejandro; Estañ-Capell, Javier; Sáez-Martín, L.; Hernández, J.M.ª Martín

doi:10.1111/dth.13888

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…This is also believed to be the cause of ACC in babies who were papyraceous fetuses or prematurity. 12 , 15 , 16 The early death of fetuses from multiple pregnancy, which usually occurs in the late first trimester or early second trimester, releases thrombotic substance, thus promoting placenta infarction, disseminated intravascular coagulation, and then cutaneous lesions. The administration of teratogenic drugs during pregnancy, such as methimazole or valproate, was thought to be the underlying cause of ACC.…”

Section: Discussionmentioning

confidence: 99%

“…A topical antimicrobial with near-occlusive dressing can be used to reduce the risk of infection and fluid loss. 16 At the early stage, to promote epithelialization, a wet dressing was favored and should be changed frequently enough to maintain a moist enough environment. If the wound lesions exudated, wet dressings should be changed to dry dressings.…”

Section: Discussionmentioning

confidence: 99%

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Type VII Aplasia Cutis Congenita in Neonates Related to Maternal HBV Infection? Case Report and Literature Review

Li¹,

Zhang²,

Yang³

et al. 2023

CCID

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Aplasia cutis congenita (ACC) is a rare disease with an unclear pathogenic mechanism. ACC has been suggested to result from the disrupted development or degeneration of skin in the uterus. This study describes two cases that may have underlying pathogenic cause that have not been previously reported. Two neonates who were admitted to the neonatal intensive care unit due to “skin lesions on the limbs” without other deformities or complications were diagnosed with type VII ACC by dermatologist. The mothers showed positivity for hepatitis B virus (HBV) surface antigen and elevated level of HBV DNA copies, which may be related to ACC. But this association could be a coincidence. Both neonates were treated with antibacterial dressings and achieved satisfactory healing.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Type VII Aplasia Cutis Congenita in Neonates Related to Maternal HBV Infection? Case Report and Literature Review

Li¹,

Zhang²,

Yang³

et al. 2023

CCID

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“…Type I ACC is the most common type, and most of them are without underlying syndromes, malformations, or other abnormalities. Type V is rare, associated with fetus papyraceus or placental infarction, and characterized by a symmetrical and H-shaped distribution over the trunk and extremities [ 7 ]. Here, we successfully treated a patient with extensive abdominal skin defects with conservative treatment.…”

Section: Introductionmentioning

confidence: 99%

Large skin defect in Type V aplasia cutis congenita treated with conservative treatment: a case report

song,

yang,

shi

et al. 2024

BMC Pediatr

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Aplasia cutis congenita (ACC) is a congenital disorder that can be classified into nine types, with Type I ACC being the most common. Type V ACC associated with fetus papyraceus is a rare subtype of ACC. We report the case of a Type V ACC in a male newborn with extensive abdominal skin defects. The patient received conservative treatment using hydrogel foam and silicone foam dressings. Approximately five weeks later, the patient was discharged when more than 60% of the skin had completed epithelialization. After discharge from West China Second University Hospital, Chengdu , the patient continued to be followed up regularly at the Burns and Plastic Surgery Clinic at local hospital in Gansu. We followed up the child by telephone. After 4 months of follow-up, scar tissue formation was observed in the trunk area. The infant is 2 years and 5 months old now, physical examination did not reveal any organ problems.

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Safety of Silver Dressings in Infants; a Systematic Scoping Review

O’Donohoe,

Leon,

Orr

et al. 2024

Journal of Burn Care &Amp; Research

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Silver-based dressings are used to reduce infection risk and optimize conditions for wound healing. They are widely used in the management of burns and other complex wounds. However, reports of elevated serum silver and concern over systemic toxicity have meant that their use in young children has been questioned. The aim of the current study was to map the literature relating to the use of silver-based dressings in children under 1 year of age. A systematic scoping review was conducted according to the methodology described by the Joanna Briggs Institute. Sources were identified from major medical databases as well as the gray literature. Inclusion criteria were the use of silver-based dressing in children under 1 year of age. Outcomes of interest were complications or adverse events attributed to silver-based dressings and elevated serum silver levels. A total of 599 sources were identified through the search strategy, with 110 included for review. Complications were described in 31 sources, with the most frequent being wound infection. No cases of argyria, kernicterus, or methemoglobinemia were reported. Six sources documented elevated serum silver levels in infants but none reported adverse events related to this. On the basis of current evidence, we suggest reserving silver dressings in infants under 1 for wounds that are at high risk of infection. Wound area and duration of treatment should be considered when assessing the risk of systemic absorption of silver. Standardized data collection and recording of complications and adverse events is recommended to better inform future clinical decision-making.

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Type V aplasia cutis congenita in a preterm newborn successfully resolved

Cited by 3 publications

References 15 publications

Type VII Aplasia Cutis Congenita in Neonates Related to Maternal HBV Infection? Case Report and Literature Review

Type VII Aplasia Cutis Congenita in Neonates Related to Maternal HBV Infection? Case Report and Literature Review

Large skin defect in Type V aplasia cutis congenita treated with conservative treatment: a case report

Safety of Silver Dressings in Infants; a Systematic Scoping Review

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