The deformation behavior of commercially pure submicrocrystalline and coarse-grained titanium was studied at the macroscopic level. Stress-strain curves of the materials were analyzed. Time-space distributions of local strains were studied at all stages of strain hardening using speckle interferometry. The life time of test specimens of the materials and the coordinates of the fracture region were calculated theoretically and confirmed experimentally. The motion of the zones of localized plasticity was studied. The prefracture stage was shown to involve "condensation" of the zones of localized plasticity and migration of deformation to the fracture neck.Introduction. Metallic materials for medical applications must meet the following requirements: be biologically inert on exposure to aggressive media and withstand various long-term mechanical loads. It is known that the chemical elements whose atomic weight is greater than that of iron are harmful to the human organism [1]. The light metals widely used in engineering, for example, magnesium or aluminum, react vigorously with organic acids and, hence, are also unsuitable. From this point of view, titanium has a unique compatibility with organism tissues. Long-term clinical tests have shown that titanium is very suitable for use in implants and prostheses for bone and soft tissues: the structure of the tissues surrounding titanium have not changed for a long time [2]. However, an increased content of impurities, including alloying elements, considerably reduces the biocompatibility of titanium; therefore, titanium based surgical implants can be produced using only high-purity titanium.We note that the main drawbacks of pure titanium are a low wear resistance, a small elastic modulus, and an insufficient fatigue resistance, which can result, for example, in a fracture of bone screws due to torque [1]. In engineering, these problems are solved by using titanium alloys, but, as noted above, this method is undesirable for medical materials technology.The mechanical characteristics of pure titanium can be improved by producing a nanostructural (submicrocrystalline) state over the entire volume [3]. At present, bulk nanocrystalline materials are produced by methods of intense plastic deformation [3,4]; therefore, accounting for the deformation behavior of ultrafine materials is of great significance in both the manufacture of articles from them and in predicting the service behavior of the articles.In all cases, as is known, plastic deformation develops nonuniformly and is localized at the macrolevel, with the localization pattern and its evolution largely determined by characteristics such as the plasticity margin, service life, and type of fracture. Studies [5-7] using more than 20 types of single-crystalline and polycrystalline