Introduction: Differentiated development of coordination abilities in children with different strengths of the nervous system has a positive impact on the development of speed endurance. However, there are no such studies. Objective: To determine the effect of coordination training on development of coordination abilities and speed endurance abilities of children 7-8 years with different strengths of the nervous system. Method: Pedagogical research was carried out for 7 months at school with children 7-8 years, a total of 60 children taking part. All the children were admitted to physical education classes for health reasons and divided into three groups of 20 each using the method of random sampling. The study used tests that determine the level of development of coordination abilities (shuttle run), speed endurance (jump over the rope) and strengthweakness of the nervous system in the process of excitation (tapping test). The programs Bio-Stat, Excel and parametric criterion T-Student were used in statistical and mathematical processing of the results. Results: After the study, new results were obtained. In children from the first group (KG) coordination abilities became worse by 0.1 seconds; at the same time, speed endurance abilities improved from 28.4±2.1 to 29.3±1.8 (p>0,05). Children in the second group (EG-1) improved their performance in the test "shuttle run"