This paper presents a process for selecting candidate Detect-and-Avoid Well Clear definitions for Unmanned Aircraft Systems and non-cooperative aircraft. The selection is based on considerations of the unmitigated collision risk, maneuver initiation range, and others. Operational assumptions related to low cost, size, weight, and power sensors equipped by the Unmanned Aircraft Systems are applied to set the scope of aircraft performance and drive metrics computation. Four candidate Well Clear definitions, two primary and two secondary, varying from 1500 to 2500 ft in their horizontal miss distance and from 0 to 25 sec in modified tau, are selected for future analyses.