Über den Wirkungsmechanismus des Insulins

The action of insulin on the perfused mammalian liver

“…During the first hour control period there is a storage of glycogen, whereas in the second hour insulin, in contrast to Exp. 4, merely stops the further deposition of glycogen. It is also seen that the samples from fresh lobes, taken at the beginning of the insulin period, contained less glycogen than the later samples from the first lobes taken at the same time.…”

The rôle of the phosphates in carbohydrate metabolism in skeletal muscle

“…Harrop and Benedict(9), Andova and Wagner(io), and Kay and Rob ins on(11) have found an increase in the hexosephosphate of muscle after insulin, while others, Soxhey and Allen(12), Collazo and others (13), and Eadie, Macleod and Noble(14) have usually found a slight decrease. The results evidently differ with the condition of the insulinised rabbits, whether well nourished or starving, with or without convulsions, etc.…”