Über die Cholesterinbildung im Tierkörper

Beumer, H.; Lehmann, Fr.

doi:10.1007/bf02609161

Cited by 51 publications

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“…Stepp (180) reported that pigeons could synthesize cholesterol. Beumer and Lehmann (181) in experiments with new born puppies found that the increase in bodily cholesterol was equal to twenty times the amount in the food. Similar results have been obtained by Knudson (182) with rats.…”

Section: Acid Intoxicationmentioning

confidence: 94%

Biochemistry of the Fats.

Bloor¹

1925

Chem. Rev.

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Section: Acid Intoxicationmentioning

confidence: 94%

Biochemistry of the Fats.

Bloor¹

1925

Chem. Rev.

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“…That such synthesis does take place has been shown by the study of the relative growth and cholesterol content of infants' brain and by experiments with dogs by Beumer and Lehmann [1923], and with rats by Channon [1925] and by Randles and Knudson [1925]. Beumer [1923] goes so far as to advance the view that cholesterol is not to be considered as a food in any sense of the term but that in metabolism it plays a part more comparable with the role of the purines, in the sense that the cholesterol excreted by the organism is the true residuum, unrequired by the body, of the metabolic processes and is derived like uric acid from endogenous and exogenous sources. Whatever may be the truth of this conception it does not appear to us to modify the views previously maintained by Gardner in former papers of the nature of the cholesterol cycle.…”

Section: By John Addyman Gardner and Hugh Gainsboroughmentioning

confidence: 99%

Studies on the Cholesterol Content of Normal Human Plasma. Part I

Gardner

Gainsborough

1927

Biochemical Journal

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DURING the past 20 years a very large number of observations have been published on the total cholesterol content of blood or of serum from pathological cases. As a result, the blood picture is described, in any one case, as a hypercholesterolaemia or a hypocholesterolaemia, in comparison to a socalled normal value of total cholesterol in human blood. It is, however, to be noted that relatively few determinations have been made on normal subjects, and that values of the normal, obtained from these sparse data-not too concordant in the different researches-have been quoted from author to author.It is generally agreed that in certain forms of nephritis, irregularly in diabetes mellitus and also in the later months of pregnancy, a hypercholesterolaemia is found, and that in infective conditions a hypocholesterolaemia occurs. As regards other diseases it is impossible in the present state of our knowledge of the physiological limits of cholesterol content of the blood to decide if there is any constant alteration in the level of this value. Denis [1917] considers that at present the total cholesterol content of the blood is practically of no diagnostic significance.Though much work has been done on the total cholesterol content of blood or serum, comparatively little attention has been directed to the relative amounts of so-called free or non-esterified cholesterol and cholesterol in ester form. This unfortunate position is to some extent explained by the historical development of our knowledge of this subject. Fat, cholesterol and allied substances were obtained together by the extraction of tissues and fluids of the body by means of ether and other solvents, and in early days no effective methods were available for differentiating, quantitatively at any rate, between free and ester cholesterol. Consequently cholesterol came to be regarded as intimately connected with fat metabolism.This idea has persisted throughout the history of the subject and has been upheld largely by the French observers. Terroine [1919] considers that there is a constant lipaemic coefficient, i.e. a constant ratio of total cholesterol to total fatty acid in individual animals. Chauffard and his school [1920]

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Acholic Cachexia

Bissell¹

1936

Arch Surg

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Über die Cholesterinbildung im Tierkörper

Cited by 51 publications

References 0 publications

Biochemistry of the Fats.

Biochemistry of the Fats.

Studies on the Cholesterol Content of Normal Human Plasma. Part I

Acholic Cachexia

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