Über die Paralyse des Nervus abducens bei Otitis

Gradenigo, G.

doi:10.1007/bf01930369

Cited by 99 publications

(58 citation statements)

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“…Dorello explained that the paralysis of the nerve is only temporary and disappears soon after the localized compression is relieved, leaving behind little to no permanent damage. 19,20,23,56 In the following years several others, such as Baldenweck 7 and Baratoux, 8 published anatomical reports and reviews of the literature that supported Dorello's ideas regarding the temporary paralysis of the abducent. 7,8,20 Nevertheless, Gradenigo, who responded to these new advancements in his 1907 review of various case reports on acute abducent paralysis in otitis media, was staunch in insisting that Dorello's findings were flawed:…”

Section: Giuseppe Gradenigo (1859-1926)mentioning

confidence: 98%

“…Now, suppose that the lesion of the abducens occurs along with acute purulent otitis media in the area of the top of the pyramid, is the mechanism [of infection and abducent paralysis] the same?] 23 Gradenigo continues this discussion with a series of questions and challenges to Dorello's hypothesis. Nevertheless, his early critical summary of Dorello's work was so accurate and concisely written that it was translated and quoted by Harris Vail to form the body of his 1922 publication on Dorello's canal.…”

Section: Giuseppe Gradenigo (1859-1926)mentioning

confidence: 99%

“…The veins of the tympanic cavity belong to the district of the pharyngeal plexus, of the meningea media vein, of the internal and external jugular vein and, consequently, have no direct relationship with the inferior petrosal sinus … Dorello's hypothesis is eventually unable to explain the observed deaths with symptoms of leptomeningitis.] 23 Gradenigo doubted the accuracy of Dorello's descriptions and denied that the tympanic veins had any direct relationship with the inferior petrosal sinus, among other criticisms. 23 In a recent paper, Felisati and Sperati relate that, in an astute response, Dorello referred Gradenigo to the anatomical findings of Politzer, Gradenigo's own mentor.…”

Section: Giuseppe Gradenigo (1859-1926)mentioning

confidence: 99%

“…23 Gradenigo doubted the accuracy of Dorello's descriptions and denied that the tympanic veins had any direct relationship with the inferior petrosal sinus, among other criticisms. 23 In a recent paper, Felisati and Sperati relate that, in an astute response, Dorello referred Gradenigo to the anatomical findings of Politzer, Gradenigo's own mentor. 20 In his studies of the human ear, Politzer found that the vasculature of the middle ear and tympanic cavity was indeed related to the petrosal sinus, a finding that had since been confirmed by other published anatomical texts.…”

Section: Giuseppe Gradenigo (1859-1926)mentioning

confidence: 99%

“…31 Thus, through his keen perception, Gruber noticed the importance of the canal and set the stage for future investigations of this structure-the most critical of which would arise nearly 50 years later in Italy in the form of a debate between an experienced otologist, Giuseppe Gradenigo, and a budding anatomist, Primo Dorello. 19,23 Following up on his studies of cranial anatomy, in 1869 Gruber published other works on the study of the skull base. 28,30 However, Gruber's anatomical interests extended well beyond the skull.…”

Section: Wenzel Leopold Gruber (1814-1889)mentioning

confidence: 99%

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Gruber, Gradenigo, Dorello, and Vail: key personalities in the historical evolution and modern-day understanding of Dorello’s canal

Reddy¹,

Reddy²,

Jyung

et al. 2016

JNS

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A century ago an ambitious young anatomist in Rome, Primo Dorello, who sought to understand the cause of abducent nerve palsy that often occurred in patients with severe middle ear infections, conducted intricate studies on the intracranial course of the nerve. In his findings, he identified that the abducent nerve passes through a narrow sinus near the apex of the petrous bone, which formed an osteofibrous canal. Dorello suggested that in this enclosed region the abducent nerve may be particularly vulnerable to compression due to the vascular edema accompanying the infection. Although his work was widely appreciated, it was not well received by all. Interestingly, Giuseppe Gradenigo, one of the most prominent Italian otologists of the early 20th century, who was known for his work on a triad of symptoms (Gradenigo’s syndrome) that accompanies petrous apicitis, a result of severe middle ear infections, was obstinate in his criticism of Dorello’s findings. Thus a scientific duel began, with a series of correspondence between these two academics—one who was relatively new to the otological community (Dorello) and one who was well reputed in that community (Gradenigo). The disagreement ultimately ebbed in 1909, when Dorello published a report in response to Gradenigo’s criticisms and convinced Gradenigo to change his views. Today Dorello’s canal is widely recognized as a key landmark in skull base surgery of the petroclival region and holds clinical significance due to its relation to the abducent nerve and surrounding vascular structures. Yet, although academics such as Dorello and Gradenigo are recognized for their work on the canal, it is important not to forget the others throughout history who have contributed to the modern-day understanding of this anatomical structure. In fact, although the level of anatomical detail found in Dorello’s work was previously unmatched, the first description of the canal was made by the experienced Austrian anatomist Wenzel Leopold Gruber in 1859, almost 50 years prior to Dorello’s landmark publication. Another critical figure in building the understanding of Dorello’s canal was Harris Holmes Vail, a young otolaryngologist from Harvard Medical School, who in 1922 became the first person to describe Dorello’s canal in the English language. Vail conducted his own detailed anatomical studies on cadavers, and his publication not only reaffirmed Dorello’s findings but also immortalized the eponym used today—“Dorello’s canal.” In this article the authors review the life and contributions of Gruber, Dorello, Gradenigo, and Vail, four men who played a critical role in the discovery of Dorello’s canal and paved the way toward the current understanding of the canal as a key clinical and surgical entity.

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Section: Giuseppe Gradenigo (1859-1926)mentioning

confidence: 98%

Section: Giuseppe Gradenigo (1859-1926)mentioning

confidence: 99%