“…These observations are supported by other experimental and practical experience. The literature contains several reports showing that after being exposed to a species of mosquitoes by which they have not been previously bitten, human beings at first react very strongly, later on in a lesser degree or not at all (Daivson mitiams (1896-97), Morse (1896-97), Nuttall & Shipley (1901-03), Hase (1916), Gordon (1922) and Pawlowsky (1927)), Similar observations have been reported in the case of Phlebotomus by Newstead , Doerr & Russ (1913) and Boycott (1928). The last-mentioned author finds immediate as well as delayed reactions in a person who has been previously exposed to bites by Phlebotomus, while 4 unexposed persons gave no reactions at first to the bites of this species of mosquito, but at the end of 12 days exhibit a typical response.…”