Embryonics, a branch of bio-inspired hardware, is a circuit with self-healing capability. Aiming at solving the problems of low efficiency, complexity and etc. during cellular communicating in Embryonics, inspired by the transmission mechanism of hormone, a new type of four-layer Embryonics based on NoC and neighborhood connections is presented in the paper. Operational mechanism and hierarchical four-level self-healing capability of the Embryonics is also analyzed in detail. The proposed Embryonics provides a new approach for self-healing electronic systems design, which may be used in self-healing machine design.