UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia L.) ASAL KABUPATEN MELAWI PROVINSI KALIMANTAN BARAT DENGAN METODE DPPH

Puspita, Weni; Sari, Dina Yuspita; Rahman, Ika Ristia

doi:10.36387/jifi.v3i2.532

Cited by 3 publications

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“…Penggunaan sebagai obat tradisional tanaman buas-buas oleh masyarakat digunakan untuk masuk angin, bau nafas, infeksi cacing, dan memperbanyak ASI wanita menyusui. Skrining fitokimia menunjukkan daun buas-buas memiliki metabolit sekunder seperti flavonoid, saponin, tanin, steroid/terpenoid [3].…”

Section: Pendahuluanunclassified

Isolasi Dan Identifikasi Terpenoid Fraksi Heksan Daun Premna serratifolia L. Menggunakan GC-MS

Midi Candra,

Isnindar,

Luliana

2023

JSSCR

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Buas-buas (Premna serratifolia L.) is a plant that belongs to the Verbenaceae family. Terpenoid compounds that exist in buas-buas plants have bioactivity as medicine. Terpenoid compounds are soluble compounds in n-hexane. The purpose of this study was to isolate and identify the terpenoid compounds contained in the n-hexane fraction of buas-buas leaves using the GC-MS method. The buas-buas leaves were macerated with 96% ethanol solvent and then fractionated using a separating funnel with n-hexane as solvent. The n-hexane fraction of buas-buas leaves was isolated using column chromatography with a gradient mobile phase combination of n-hexane and ethyl acetate, then identified using the GC-MS instrument. The terpenoid compounds found in the n-hexane fraction of buas-buas leaves are estimated to be neophytadiene; 3,7,11,15-tetramethyl-2-hexadecen-1-ol; and 2 hydroxy-4a,5-dimethyl-3-(prop-1-en-2-yl) octahydronaphthalen-1-(2H)-one.

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Section: Pendahuluanunclassified

Isolasi Dan Identifikasi Terpenoid Fraksi Heksan Daun Premna serratifolia L. Menggunakan GC-MS

Midi Candra,

Isnindar,

Luliana

2023

JSSCR

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“…Research states that Premna serratifolia L. leaves contain secondary metabolites of flavonoids, saponins, tannins, and triterpenoids/steroids, where flavonoids are known to have properties as free radical scavengers or antioxidants, inhibitors of hydrolysis and oxidative enzymes, and work as an antiinflammatory (Liya, 2016). Puspita, W., et al (2020) stated that the ethanol extract of Premna serratifolia L. leaves a very high antioxidant activity with an IC50 value of 20.66 μg/mL. Antioxidants for facial skincare would be better *Corresponding author : Weni Puspita Email : weni.puspita.apt@gmail.com formulated in a topical form than oral because the active substances will interact longer with facial skin (Sutriningsih et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

Physical Stability and Antioxidant Activity of Pee-Off Gel Mask Ethanol Extract of Buas-buas Leaf (Premna serratifolia L.)

Puspita¹,

Puspasari²

2022

Trad.Med.J

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This study aims to determine the physical stability and antioxidant activity of peel-off gel mask ethanol extract of buas-buas leaf (Premna serratifolia L.). The ethanol extract of buas-buas leaves was obtained by maceration using 70% ethanol solvent, then concentrated using a rotary evaporator to get a thick extract. Formulation EEDB into a peel-off gel mask with a concentration of each EEDB (FI: 1%, FII: 2%, FIII : 3%). The EEDB peel-off gel mask formula was tested for physical stability by cycling test method using a climatic chamber at a temperature of 40°C ± 2°C and 4°C ± 2°C for six cycles. The tests included organoleptic, homogeneity, viscosity, pH, spreadability, and drying time. An antioxidant test was carried out using the DPPH method. The results of the physical stability test on the three EEDB peel-off gel mask formulas (FI: 1%, FII: 2%, FIII: 3%) showed good physical stability because there was no significant difference during six storage cycles (P>0.05) with the results of the preparation have a characteristic aroma of oleum citri, brownish-green in color, have a thick, homogeneous texture, meet the requirements of pH, viscosity, spreadability, and drying time. The stability test results of the antioxidant activity of the peel-off gel mask EEDB in the three formulas showed no significant change (P>0.05). The antioxidant activity during six storage cycles with the highest average percent inhibition before and after the cycling test, namely in Formula III, was 77.20 ± 0.28%.

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“…The ethanol extract of bebuas leaves contains flavonoid compounds which are known to have antioxidant properties and ward off free radicals. Based on the results of the research conducted by Puspita et al, it can be concluded that the ethanol extract of P. serratifolia leave has a very high antioxidant activity with an IC 50 potential of 20.66 g/mL antioxidant activity15 .…”

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confidence: 99%

“…Premna serratifolia L. contains secondary metabolites of flavonoids, saponins, tannins, and triterpenoids/steroids 15 . Methanol extract of P. serratifolia ripe fruit contains saponins, polyphenols, flavonoids, and terpenoids-steroid compounds.…”

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confidence: 99%

Phytochemistry and Pharmacological Potentials of Premna serratifolia L.: Traditional Medicinal Plant Used by Local People in Kalimantan

Khairunnisa

Febriyanti²,

Muhaimin³

2022

ijbp

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Millions of people worldwide have been using herbal medicines for thousands of years, due to their great interest in traditional medicines. One of the plants in Indonesia which has medicinal properties but is not widely known by the public and used is Bebuas plant. Bebuas (Premna serratifolia Linn) has been observed growing in West Kalimantan. The people of West Kalimantan used bebuas leaves to reduce cholesterol levels, the young leaves used as a traditional medicine to expel wind in the body quickly, treat intestinal worms, and increase breast milk for nursing mothers, and the decoction of fresh leaves is used for colds and fever medicine. Several studies report bebuas (Premna serratifolia L.) had many pharmacological activities. Bebuas contains flavonoids, saponins, tannins and triterpenoids/steroids that have a role in pharmacological activity. The present review aims to summarize the current state of scientific evidence on the pharmacological potentials of P. serratifolia. The subject of literature published from 2012 to 2022 were obtained frominternational research databases including PubMed, Google Scholar, EBSCO, SCOPUS, and Cochrane, using the keywords Premna serratifolia L., traditional medicine, medicinal plants, and pharmacology. The pharmacological activities which are discussed further in the review including antioxidant, anti-arthritic, anticholesterol, anti-inflammatory, antimicrobial, antihelmintic, antidiabetic, and anticancer/cytotoxic. The study suggests that Premna serratifolia L. is a potent source for further development of phytomedicine.

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UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL DAUN BUAS-BUAS (Premna serratifolia L.) ASAL KABUPATEN MELAWI PROVINSI KALIMANTAN BARAT DENGAN METODE DPPH

Cited by 3 publications

References 0 publications

Isolasi Dan Identifikasi Terpenoid Fraksi Heksan Daun Premna serratifolia L. Menggunakan GC-MS

Isolasi Dan Identifikasi Terpenoid Fraksi Heksan Daun Premna serratifolia L. Menggunakan GC-MS

Physical Stability and Antioxidant Activity of Pee-Off Gel Mask Ethanol Extract of Buas-buas Leaf (Premna serratifolia L.)

Phytochemistry and Pharmacological Potentials of Premna serratifolia L.: Traditional Medicinal Plant Used by Local People in Kalimantan

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