UK guidance for non-heart-beating donation

Ridley, S.; Bonner, Stephen; Bray, Kate; Falvey, Sue; Mackay, Jonathan H.; Manara, Alex

doi:10.1093/bja/aei235

Cited by 55 publications

(32 citation statements)

References 5 publications

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“…Despite early transplantation being largely from DCD, the mainstay of transplantation has been from DBD. It has only been since the end of the century following the definition of the categories of DCD by the International Congress on Non-Heart Beating Donation that transplant programmes have seriously considered DCD organs to expand the donor pool (2,3).…”

Section: The Potential For Dcd Heart Donationmentioning

confidence: 99%

Heart transplantation from donation after circulatory determined death

Page¹,

Messer²,

Large³

2018

Ann. Cardiothorac. Surg.

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Fifty years since the first successful human heart transplant from a non-heart beating donor, this concept of heart transplantation from donation after circulatory determined death (DCD) promises to be one of the most exciting developments in heart transplantation. Heart transplantation has established itself as the best therapeutic option for patients with end-stage heart failure, with the opportunity to provide these patients with a near-normal quality of life. However, this treatment is severely limited by the availability of suitable donor hearts. In recent times, heart transplantation has been limited to using donor hearts from donors following brain stem death. The use of donor hearts from DCD had been thought to be associated with high risk and poor outcomes until recent developments in organ perfusion and retrieval techniques have shown that this valuable resource may provide an answer to the global shortage of suitable donor hearts. With established DCD heart transplant programmes reporting encouraging results, this technique has been shown to be comparable to the current gold standard of donation after brain death (DBD) heart transplantation.

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Section: The Potential For Dcd Heart Donationmentioning

confidence: 99%

Heart transplantation from donation after circulatory determined death

Page¹,

Messer²,

Large³

2018

Ann. Cardiothorac. Surg.

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“…While no national guidelines exist specifically for NHBD in the paediatric population, guidelines have been published by The Intensive Care Society and British Transplantation Society 21 22. We suggest that specific guidelines need to be adapted for the PICU population since the case-mix of patients is very different and the challenges relating to small infants untested.…”

Section: Discussionmentioning

confidence: 99%

The potential for non-heart beating organ donation within a paediatric intensive care unit

Fraser

Thomas

Fish

et al. 2010

Archives of Disease in Childhood

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“…Thus, they described the case of a deceased patient who, after the diagnosis of cardiac death (made in accordance with both recent guidance from the Academy of Medical Royal Colleges and existing NHBOD programs), [3][4][5] was transferred to the operative theater, whereupon a median sternotomy was performed and cardiopulmonary bypass established. Thus, they described the case of a deceased patient who, after the diagnosis of cardiac death (made in accordance with both recent guidance from the Academy of Medical Royal Colleges and existing NHBOD programs), [3][4][5] was transferred to the operative theater, whereupon a median sternotomy was performed and cardiopulmonary bypass established.…”

Section: To the Editormentioning

confidence: 99%