2023
DOI: 10.7759/cureus.46429
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Ulcerative Colitis Flare Post Isotretinoin Use: A Case Report

Maha AlHussein,
Abdulaziz H AlHussain

Abstract: Ulcerative colitis (UC) is an inflammatory bowel disease characterized by chronic intestinal inflammation. We present a case of UC flare induced by isotretinoin, a medication commonly used for the treatment of severe acne. A 36-year-old male with a history of UC in remission presented with moderate-severe cystic acne and was started on isotretinoin. After four months of treatment, he developed symptoms of UC flare, including bloody diarrhea. A colonoscopy revealed ulcerative pancolitis, and isotretinoin was di… Show more

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