2010
DOI: 10.1097/aog.0b013e3181c8e2aa
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Ulipristal Acetate Taken 48–120 Hours After Intercourse for Emergency Contraception

Abstract: II.

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Cited by 141 publications
(90 citation statements)
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References 12 publications
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“…44,134 Ulipristal acetate may have greater effectiveness than oral levonorgestrel at the end of the 5-day window of use, and its remaining effectiveness and adverse effect profile are similar to those of levonorgestrel. 135,136 In addition, on the basis of recent data about lower efficacy of levonorgestrel EC, ulipristal may be more effective in people who weigh more than 165 pounds. 137,138 Placement of a copper-bearing IUD is less commonly used for EC in adolescents but is the most effective EC method, with a failure rate of less than 1%.…”
Section: Emergency Contraceptionmentioning
confidence: 99%
“…44,134 Ulipristal acetate may have greater effectiveness than oral levonorgestrel at the end of the 5-day window of use, and its remaining effectiveness and adverse effect profile are similar to those of levonorgestrel. 135,136 In addition, on the basis of recent data about lower efficacy of levonorgestrel EC, ulipristal may be more effective in people who weigh more than 165 pounds. 137,138 Placement of a copper-bearing IUD is less commonly used for EC in adolescents but is the most effective EC method, with a failure rate of less than 1%.…”
Section: Emergency Contraceptionmentioning
confidence: 99%
“…Data suggest that ulipristal acetate, approved by the FDA in 2010, may have increased effectiveness over oral levonorgestrel at the end of the 5-day window of use and in heavier women. [208][209][210] On the basis of data demonstrating that the levonorgestrel EC pill loses effectiveness in women who weigh more than 165 pounds and is ineffective in women who weigh more than 176 pounds, the levonorgestrel EC pill is undergoing revised labeling in Europe, and the FDA is considering whether to require similar revisions in the United States. 211 Unlike ulipristal, which is pregnancy category X, levonorgestrel does not have teratogenic or other adverse effects on the fetus, 212 and a pregnancy test is not necessary before prescribing levonorgestrel EC.…”
Section: Male Condomsmentioning
confidence: 99%
“…Gebelik oranları UPA grubunda %1,8 ve LNG grubunda %2,6 bulunmuştur ve sonuç olarak UPA anlamlı olarak daha fazla gebeliği önlemiştir şeklinde rapor edilmiştir 34 . Fine ve arkadaşlarının yayınladıkları prospektif, faz 3 çalışmada; UPA korunmasız cinsel ilişkiden sonraki 48-120 saatler arası kullanılmış ve buna rağmen beklenen gebelik oranının %5,5'ten %2,1'e düştüğü görülmüş; UPA korunmasız cinsel ilişkiden 120 saat sonrasına kadar kullanılabilinir şeklinde sonuç belirtilmiştir 35 . Klinik çalışmalardan da anlaşılacağı üzere UPA, LNG'den daha etkin bir acil kontraseptiftir (Tablo1).…”
Section: Mifepristonunclassified
“…UPA kullanımında görülen yan etkiler; baş ağrısı (%18), bulantı (%12), karın ağrısı (%12), daha az görülen yan etkiler ise adet sancısı, yorgunluk, baş dönmesi olarak sıralanabilir. Diğer bir yan etkisi menstruasyondaki gecikmedir 34,35 . Gebelikte fetus üzerine etkileri hakkında yeterli veri yoktur, hayvan çalışmalarında teratojenik etki saptanmamıştır.…”
Section: Mifepristonunclassified