Ultra-High-Molecular-Weight-Polyethylene (UHMWPE) as a Promising Polymer Material for Biomedical Applications: A Concise Review

Hussain, Muzamil; Naqvi, Rizwan Ali; Abbas, Naseem; Khan, Shahzad Masood; Nawaz, Saira; Hussain, Arif; Zahra, Nida; Khalid, Muhammad Waqas

doi:10.3390/polym12020323

Cited by 150 publications

(91 citation statements)

References 184 publications

(201 reference statements)

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“…One of the case material couple simulated using Ansys software is CoCr alloy and Ti6Al4V for cup and femoral head component, respectively. However, the concern of (Anderson et al, 2004;Pulgarin and Albano, 2015) 380,000 0.26 500-1,700 2 CoCr (Al Jabbari, 2014;Puccio and Mattei, 2015) 230,000 0.3 280-380 3 SS316L (Yildiz et al, 2011;Naik et al, 2020) 200,000 0.3 190 4 UHMWPE (Puccio and Mattei, 2015;Hussain et al, 2020) 1,000 0.4 4-6 this research is not in MoM materials, where it investigated mixed material couples. The last conclusion showed that least wear when using the CoCr alloy on the ultra-high molecular weight polyethylene (UHMWPE) material.…”

Section: Introductionmentioning

confidence: 97%

Reducing Contact Stress of the Surface by Modifying Different Hardness of Femoral Head and Cup in Hip Prosthesis

et al. 2021

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The wear of hip prosthesis due to applied load and sliding distance during the patient's daily activity cannot be avoided. Wear causes osteolysis or metallosis due to the wear debris produced by the wear process. Several methods were used to reduce wear in metal-on-metal hip prostheses. One of the efforts performed to reduce wear was the differential-hardness concept. Based on the literature, the fine surface roughness of the femoral head are the reason why the hip prosthesis with differential-hardness reduces wear. Besides, the differential-hardness will contribute to the difference of modulus elasticity then influenced the contact stress on the surface contact. According to Archard's wear law, wear on the material pair is affected by contact stress. Therefore, the analysis of contact stress on the hip prosthesis with differential-hardness is important to investigate. The investigation performed by the static contact of two-dimensional axisymmetric with frictionless by using finite element simulation. The simulated models are the alumina vs. alumina, alumina vs. SS316L, CoCr vs. CoCr, CoCr vs. SS316L, and SS316L vs. UHMWPE. The purpose of this study is to determine the contact stress on the surface contact due to differential-hardness of the femoral head and cup. The results of simulations show that the differential-hardness marked by differences in the modulus of elasticity can reduce the contact stress on the surface contact if compare with the similar hardness.

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Section: Introductionmentioning

confidence: 97%

Reducing Contact Stress of the Surface by Modifying Different Hardness of Femoral Head and Cup in Hip Prosthesis

et al. 2021

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“…Moreover, it also has the highest impact resistance among all the polymers, which makes it an excellent candidate for biomedical applications. Numerous attempts have been made to use pristine UHMWPE or UHMWPE composites in the bulk form in biomedical applications [ 77 ]. However, there are very few studies where efforts have been made to explore the feasibility of using UHMWPE in the form of coatings in biomedical applications.…”

Section: Uhmwpe Coatings For Different Applicationsmentioning

confidence: 99%

Recent Advances in UHMWPE/UHMWPE Nanocomposite/UHMWPE Hybrid Nanocomposite Polymer Coatings for Tribological Applications: A Comprehensive Review

Samad

2021

Polymers

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In the recent past, polymer coatings have gained the attention of many researchers due to their low cost, their ability to be coated easily on different substrates, low friction and good anti-corrosion properties. Various polymers such as polytetrafluroethylene (PTFE), polyether ether ketone (PEEK), polymethylmethacrylate (PMMA), polyurethane (PU), polyamide (PA), epoxy and ultra-high molecular weight polytheylene (UHMWPE) have been used to develop these coatings to modify the surfaces of different components to protect them from wear and corrosion. However, among all these polymers, UHMWPE stands out as a tribologist’s polymer due to its low friction and high wear resistance. These coatings have found their way into applications ranging from microelectro mechanical systems (MEMS) to demanding tribological applications such as bearings and biomedical applications. Despite its excellent tribological properties, UHMWPE suffers from limitations such as low load bearing capacity and low thermal stability. To overcome these challenges researchers have developed various routes such as developing UHMWPE composite and hybrid composite coatings with several types of nano/micro fillers, developing composite films system and developing dual film systems. The present paper is an effort to summarize these various routes adopted by different researchers to improve the tribological performance of UHMWPE coatings.

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“…Hydrogels based on polysaccharides and their hybrids show great promise for wound healing and cartilage regeneration [2]. Due to its low friction, high wear resistance, toughness, durability, ductility and biocompatibility, an ultra-high molecular weight polyethylene (UHMWPE) has found its way into numerous biomedical applications both in its bulk form, and in the form of coatings [3][4][5], especially as implants (total hip arthroplasty, joint implants, bone tissue engineering). Porous UHMWPE with high osteogenous properties has been successfully used to simulate cancellous-bone tissue [6].…”

Section: Introduction 1polymeric Materials For Biomedical Applicatiomentioning

confidence: 99%

CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review

et al. 2021

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The development of advanced composite biomaterials combining the versatility and biodegradability of polymers and the unique characteristics of metal oxide nanoparticles unveils new horizons in emerging biomedical applications, including tissue regeneration, drug delivery and gene therapy, theranostics and medical imaging. Nanocrystalline cerium(IV) oxide, or nanoceria, stands out from a crowd of other metal oxides as being a truly unique material, showing great potential in biomedicine due to its low systemic toxicity and numerous beneficial effects on living systems. The combination of nanoceria with new generations of biomedical polymers, such as PolyHEMA (poly(2-hydroxyethyl methacrylate)-based hydrogels, electrospun nanofibrous polycaprolactone or natural-based chitosan or cellulose, helps to expand the prospective area of applications by facilitating their bioavailability and averting potential negative effects. This review describes recent advances in biomedical polymeric material practices, highlights up-to-the-minute cerium oxide nanoparticle applications, as well as polymer-nanoceria composites, and aims to address the question: how can nanoceria enhance the biomedical potential of modern polymeric materials?

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Ultra-High-Molecular-Weight-Polyethylene (UHMWPE) as a Promising Polymer Material for Biomedical Applications: A Concise Review

Cited by 150 publications

References 184 publications

Reducing Contact Stress of the Surface by Modifying Different Hardness of Femoral Head and Cup in Hip Prosthesis

Reducing Contact Stress of the Surface by Modifying Different Hardness of Femoral Head and Cup in Hip Prosthesis

Recent Advances in UHMWPE/UHMWPE Nanocomposite/UHMWPE Hybrid Nanocomposite Polymer Coatings for Tribological Applications: A Comprehensive Review

CeO2 Nanoparticle-Containing Polymers for Biomedical Applications: A Review

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