To weaken the harm of Al-Si coating and increase the strength of welded joint, variable thickness of Ni foil (Ni, an austenitic formation element) was added into the lap laser welding Al-Si coated 22MnB5 hot stamping steel/galvanized steel joints. The joints' weld appearance, microstructure, and mechanical properties were explored. The weld altered from X-shape to Y-shape with the increased thickness of Ni foil. During welding, Al-Si coating was melted and diluted into the welding pool, forming δ-ferrite (a rich-Al phase with low toughness and strength) in FZ and FB. This phase deteriorated the strength of the joints. After adding Ni, the amount and size of the δ-ferrite phase decreased. With a significant thickness of Ni foil, δ-ferrite would disappear. However, a new phase (FM, rich-Ni phase) probably formed except PM(a no or negligible Ni phase). The heat-affected zone (HAZ) on the side of 22MnB5 comprised a coarse martensite zone, refined martensite zone, martensite+ferrite zone, and tempered martensite zone from the FZ to the basic material. HAZ on the side of galvanized steel mainly contained ferrite and pearlite. After adding Ni foil, the strength of the joint was more than that without Ni. The maximum strength of the joint can be up to 679MPa because of the disappearance of δ-ferrite. Meanwhile, the toughness of the joint increased. The fracture mode was from three mixed fractures(cleavage, quasi-cleavage, and dimple) to one fracture(dimple).