2023
DOI: 10.1002/adfm.202313806
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Ultra‐Small ATP‐Decorated Gold Nanoparticles for Targeting Amyloid Fibrils in Neurodegenerative Diseases

Vijay Bhooshan Kumar,
Vijay Kumar,
Sourav Kumar
et al.

Abstract: Ultrafine Gold nanoparticles (Au NPs) functionalized with various biomolecules constitute an alternative to antibodies as anti‐amyloidogenic agents. However, generating stable ultrafine Au NPs with high surface activity is challenging. Here, the capacity of phosphate groups in biomolecules is used to stabilize Au NPs. The characteristics of Au NPs decorated with adenosine mono‐, di‐, and tri‐phosphate are compared as well as adenosine and peptide nucleic acid‐containing adenosine as controls. Among them, ATP‐A… Show more

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