The main objective of this chapter is to introduce to the readers the issue of head and neck pain, temporomandibular joint (TMJ) disorders, clicking, headaches, migraines, and neck discomfort that are likely to present in the clinic with similar signs and symptoms. This chapter deals with the introduction, clinical examination, investigation, and the use of splint therapy, muscle complex injection therapy with botox and prolotherapy, TMJ lavage, arthrocentesis, and TMJ surgery to treat such patients.Headaches, Migraine, and TMJ Pain Management: Medical and Surgical Intervention http://dx.doi.org/10.5772/63381 113 Figure 3. An MRI coronal view of a patient with left TMJ pain and hypomobility. The view shows left disk displacement toward the anterior-medial aspect.