Ultra-widefield handheld swept-source OCT for peripheral retinal imaging

Ni, Shuibin; Nguyen, Thanh-Tin P.; Ng, Ringo; Khan, Shanjida; Ostmo, Susan; Jia, Yali; Chiange, Michael F.; Huang, David; Campbell, J. Peter; Jian, Yifan

doi:10.1117/12.2608284

“…Several research groups, including ours, have been pioneering the development of faster OCT prototypes optimized for neonatal use. We are the only group to have successfully achieved ultra-widefield OCT imaging in non-sedated babies [23,24,33]. Our previously reported panretinal OCT imaging system, notable for its extensive FOV in a single capture, has proven effective in diagnosing various pediatric retinal diseases.…”

Section: Discussionmentioning

confidence: 99%

“…Our earlier systems encountered challenges such as limited imaging speed and suboptimal optical design, which impeded the integration of OCTA mode in ultrawide imaging [23,24,35]. In this study, however, we have addressed these limitations by developing a faster OCT engine with improved optical performance.…”

Section: Discussionmentioning

confidence: 99%

Panretinal handheld OCT angiography for pediatric retinal imaging

Ni,

LIANG,

Ng

et al. 2024

Preprint

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Comprehensive visualization of retina morphology is essential in the diagnosis and management of retinal diseases in pediatric populations. Conventional imaging techniques often face challenges in effectively capturing the peripheral retina, primarily due to the limitations in current optical designs, which lack the necessary field of view to characterize the far periphery. To address this gap, our study introduces a novel ultra-widefield optical coherence tomography angiography (OCTA) system. This system, specifically tailored for pediatric applications, incorporates an ultrahigh-speed 800 kHz swept-source laser. The system’s innovative design achieves a 140° field of view while maintaining excellent optical performance. Over the last 15 months, we have conducted 379 eye examinations on 96 babies using this system. It demonstrates marked efficacy in the diagnosis of retinopathy of prematurity, providing detailed and comprehensive peripheral retinal angiography. The capabilities of the ultra-widefield handheld OCTA system in enhancing the clarity and thoroughness of retina vascularization assessments have significantly improved the precision of diagnoses and the customization of treatment strategies. Our findings underscore the system’s potential to advance pediatric ophthalmology and broaden the scope of retinal imaging.

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“…Our earlier systems encountered challenges such as limited imaging speed and suboptimal optical design, which impeded the integration of OCTA mode in ultrawide imaging [ 26 , 27 , 40 ]. In this study, however, we have addressed these limitations by developing a faster OCT engine with improved optical performance.…”

Section: Discussionmentioning

confidence: 99%

Panretinal handheld OCT angiography for pediatric retinal imaging

Ni,

Liang,

Ng

et al. 2024

Biomed. Opt. Express

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Comprehensive visualization of retina morphology is essential in the diagnosis and management of retinal diseases in pediatric populations. Conventional imaging techniques often face challenges in effectively capturing the peripheral retina, primarily due to the limitations in current optical designs, which lack the necessary field of view to characterize the far periphery. To address this gap, our study introduces a novel ultra-widefield optical coherence tomography angiography (OCTA) system. This system, specifically tailored for pediatric applications, incorporates an ultrahigh-speed 800 kHz swept-source laser. The system’s innovative design achieves a 140° field of view while maintaining excellent optical performance. Over the last 15 months, we have conducted 379 eye examinations on 96 babies using this system. It demonstrates marked efficacy in the diagnosis of retinopathy of prematurity, providing detailed and comprehensive peripheral retinal angiography. The capabilities of the ultra-widefield handheld OCTA system in enhancing the clarity and thoroughness of retina vascularization assessments have significantly improved the precision of diagnoses and the customization of treatment strategies. Our findings underscore the system’s potential to advance pediatric ophthalmology and broaden the scope of retinal imaging.

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“…We refined the optical design of our contact handheld OCT system to achieve a 140° FOV based on our previous systems [7,[12][13][14]. This was accomplished by integrating customized relay lenses and a novel widefield eyepiece, resulting in improved performance as depicted in Figs.…”

Section: Methodsmentioning

confidence: 99%

Handheld swept-source OCT angiography for panretinal imaging

Ni,

Liang,

Ng

et al. 2024

Ophthalmic Technologies XXXIV

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We introduced an improved iteration of a panoramic retinal (panretinal) handheld swept-source OCT angiography (OCTA) imaging system with an 800 kHz VCSEL light source. The advanced system successfully achieved a remarkable 140° field of view (FOV, visual angle measured from the pupil plane), enabling comprehensive imaging coverage from the posterior pole to the peripheral retina in a single capture.

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Ultra-widefield handheld swept-source OCT for peripheral retinal imaging

Cited by 5 publications

References 7 publications

Panretinal handheld OCT angiography for pediatric retinal imaging

Panretinal handheld OCT angiography for pediatric retinal imaging

Panretinal handheld OCT angiography for pediatric retinal imaging

Handheld swept-source OCT angiography for panretinal imaging

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