Ultralight 3D Graphene Oxide Aerogel Decorated with Pd–Fe Nanoparticles for the Simultaneous Detection of Eight Biomolecules

Abstract

In this proof-of-concept study, an ultralight graphene oxide aerogel (GOx-Aero) decorated with bimetallic palladium−iron nanoparticles (Pd−Fe) was synthesized and immobilized on a glassy carbon electrode (GCE) for electrochemical sensor applications. The main objective of this work was to develop a sensitive electrochemical sensor capable of simultaneously detecting eight biomolecules, including ascorbic acid (AA), dopamine (DA), uric acid (UA), 8-hydroxyguanine (8HG), guanine (G), adenine (A), thymine (T), and cytosine (C). To the best of our knowledge, this is the first time that an electrochemical sensor has been able to detect eight biomolecules simultaneously. The bimetallic GOx aerogel significantly enhanced the performance of the sensor by increasing the electroactive area, conductivity, and anodic peak current response. The sensor demonstrated sharp, well-defined, and continuous oxidation peaks for all eight analytes of interest and wide linear ranges of 5.0− 1750, 0.25−100.0, 0.

An amplified electrochemical sensor employing one-step synthesized nickel–copper–zinc ferrite/carboxymethyl cellulose/graphene oxide nanosheets composite for sensitive analysis of omeprazole

“…Finally, as can be seen, no cathodic peak is observed for OMP electroreaction during the reverse scan, it can be concluded that the electrochemical reaction of OMP at the Ni 0.4 Cu 0.2 Zn 0.4 Fe 2 O 4 /CMC/GONs/GCE is totally irreversible based on scientific findings. 79 …”

“…Finally, as can be seen, no cathodic peak is observed for OMP electroreaction during the reverse scan, it can be concluded that the electrochemical reaction of OMP at the Ni 0.4 Cu 0.2 Zn 0.4 Fe 2 -O 4 /CMC/GONs/GCE is totally irreversible based on scientic ndings. 79 Also, the DPVs were recorded in 4 mM OMP on the surface of unmodied GCE, GONs/GCE, CMC/GONs/GCE, Ni 0.4 Cu 0.2 -Zn 0.4 Fe 2 O 4 /GCE and Ni 0.4 Cu 0.2 Zn 0.4 Fe 2 O 4 /CMC/GONs/GCE and shown in Fig. 5B.…”