Ultrasensitive detection of norovirus using a magnetofluoroimmunoassay based on synergic properties of gold/magnetic nanoparticle hybrid nanocomposites and quantum dots

Takemura, Kenshin; Lee, Jaewook; Suzuki, Tetsuro; Hara, Thoshimi; Abe, Fuyuki; Park, Enoch Y.

doi:10.1016/j.snb.2019.126672

Cited by 37 publications

(31 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Despite all the significant progress achieved in NNV detection over the last few years, recent advances linked to the use of nanotechnology, already reported in human and animal viruses [298][299][300][301][302][303][304][305][306], could provide a substantial improvement in these diagnostics in the near future. Different nanostructures are available at present, such as nanoparticles (NP), carbon nanotubes (CNT), dendrimers, and quantum dots (QDs) among others, and can be applied to the identification of nucleic acids, proteins and viral particles as well as antibodies [307,308].…”

Section: Diagnostic Proceduresmentioning

confidence: 99%

Betanodavirus and VER Disease: A 30-year Research Review

2020

View full text Add to dashboard Cite

The outbreaks of viral encephalopathy and retinopathy (VER), caused by nervous necrosis virus (NNV), represent one of the main infectious threats for marine aquaculture worldwide. Since the first description of the disease at the end of the 1980s, a considerable amount of research has gone into understanding the mechanisms involved in fish infection, developing reliable diagnostic methods, and control measures, and several comprehensive reviews have been published to date. This review focuses on host-virus interaction and epidemiological aspects, comprising viral distribution and transmission as well as the continuously increasing host range (177 susceptible marine species and epizootic outbreaks reported in 62 of them), with special emphasis on genotypes and the effect of global warming on NNV infection, but also including the latest findings in the NNV life cycle and virulence as well as diagnostic methods and VER disease control.

show abstract

Section: Diagnostic Proceduresmentioning

confidence: 99%

Betanodavirus and VER Disease: A 30-year Research Review

2020

View full text Add to dashboard Cite

show abstract

“…The high localized surface plasmon resonance (LSPR) effect was achieved by combining the AuNP/MNP hybrid nanocomposite with CdSeS QDs using anti-norovirus genome II antibody (Ab). This sensor system could be applied to norovirus detection in fecal samples with a detection limit of 0.48 pg/mL (Takemura et al, 2019).…”

Section: Magnetic Nanoparticlesmentioning

confidence: 99%

Application of Zero-Dimensional Nanomaterials in Biosensing

et al. 2020

View full text Add to dashboard Cite

Zero-dimensional (0D) nanomaterials, including graphene quantum dots (GQDs), carbon quantum dots (CQDs), fullerenes, inorganic quantum dots (QDs), magnetic nanoparticles (MNPs), noble metal nanoparticles, upconversion nanoparticles (UCNPs) and polymer dots (Pdots), have attracted extensive research interest in the field of biosensing in recent years. Benefiting from the ultra-small size, quantum confinement effect, excellent physical and chemical properties and good biocompatibility, 0D nanomaterials have shown great potential in ion detection, biomolecular recognition, disease diagnosis and pathogen detection. Here we first introduce the structures and properties of different 0D nanomaterials. On this basis, recent progress and application examples of 0D nanomaterials in the field of biosensing are discussed. In the last part, we summarize the research status of 0D nanomaterials in the field of biosensing and anticipate the development prospects and future challenges in this field.

show abstract

“…MNPs are also a popular choice for pathogen detection. Takemura and co-workers developed an LSPR-magnetofluoroimmunoassay (MFIA) for the ultrasensitive detection of norovirus (NoV), a pathogen responsible for infectious gastrointestinal disease, using a multifunctional nanocomposite of gold nanoparticles, magnetic nanoparticles, and CdSeS quantum dots, wherein anti-norovirus genogroup II antibody (antiNoV) conjugated the AuNP-MNP and the CdSeSQD [186]. The sensor could detect NoV-like particles (NoV-LP) in human faeces in a concentration range of 1.0 pg mL −1 –5.0 ng mL −1 with an LOD of 0.48 pg nL −1 .…”

Section: Applications Of Inorganic Nanomaterials In Healthcare Biomentioning

confidence: 99%

Nanomaterials for Healthcare Biosensing Applications

Pirzada

Altıntaş

2019

Sensors

185

View full text Add to dashboard Cite

In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field. Nanomaterials introduce versatility to the sensing platforms and may even allow mobility between different detection mechanisms. The prospect of a combination of different nanomaterials allows an exploitation of their synergistic additive and novel properties for sensor development. This paper covers more than 290 research works since 2015, elaborating the diverse roles played by various nanomaterials in the biosensing field. Hence, we provide a comprehensive review of the healthcare sensing applications of nanomaterials, covering carbon allotrope-based, inorganic, and organic nanomaterials. These sensing systems are able to detect a wide variety of clinically relevant molecules, like nucleic acids, viruses, bacteria, cancer antigens, pharmaceuticals and narcotic drugs, toxins, contaminants, as well as entire cells in various sensing media, ranging from buffers to more complex environments such as urine, blood or sputum. Thus, the latest advancements reviewed in this paper hold tremendous potential for the application of nanomaterials in the early screening of diseases and point-of-care testing.

show abstract

Ultrasensitive detection of norovirus using a magnetofluoroimmunoassay based on synergic properties of gold/magnetic nanoparticle hybrid nanocomposites and quantum dots

Cited by 37 publications

References 47 publications

Betanodavirus and VER Disease: A 30-year Research Review

Betanodavirus and VER Disease: A 30-year Research Review

Application of Zero-Dimensional Nanomaterials in Biosensing

Nanomaterials for Healthcare Biosensing Applications

Contact Info

Product

Resources

About