Ultrasensitive Ratiometric Fluorescence Bioassay for Accurate Detection of Covid-19-Specific Nucleocapsid Protein in Clinical Serum Samples Using Modified Cleavable Mesoporous SiO<sub>2</sub> Satellite-Enriched Carbon Dots

Hamd-Ghadareh, Somayeh; Salimi, Abdollah; Vaziry, Asaad

doi:10.1021/acsbiomaterials.3c00391

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Fluorometric Sensors and Devices for Biomarkers

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Fluorometric sensors and devices are important tools for the detection and measurement of biomarkers, which are indicators of biological processes and diseases. These sensors involve the emission of light from fluorescent molecules upon interaction with target biomolecules, resulting in a measurable signal. Fluorescence-based techniques, for instance, fluorescence microscopy, fluorometry, fluorescence resonance energy transfer (FRET), and fluorescent probes, enable researchers to study biological molecules with high sensitivity and specificity. Fluorometric sensors offer numerous benefits over conventional detection methods, like higher sensitivity, selectivity, versatility, and the ability to sense various biomarkers instantaneously. In this chapter, we provide an overview of the recent developments in fluorometric sensors and devices for biomarker detection, including the design principles, sensing mechanisms, and fabrication techniques for developing fluorometric sensors. The challenges and future directions of this technology are also discussed. This chapter highlights the importance of these techniques in advancing our understanding of biological systems and their potential for improving healthcare, food safety, and environmental monitoring.

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Ultrasensitive Ratiometric Fluorescence Bioassay for Accurate Detection of Covid-19-Specific Nucleocapsid Protein in Clinical Serum Samples Using Modified Cleavable Mesoporous SiO₂ Satellite-Enriched Carbon Dots

Cited by 3 publications

References 72 publications

Red/NIR C-dots: A perspective from carbon precursors, photoluminescence tuning and bioapplications

Red/NIR C-dots: A perspective from carbon precursors, photoluminescence tuning and bioapplications

Ratiometric fluorescence quantitation of amoxicillin based on CDs@Eu-MOFs incorporated 3D hydrogel using smartphone-assisted portable dual mode visual sensing

Fluorometric Sensors and Devices for Biomarkers

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Ultrasensitive Ratiometric Fluorescence Bioassay for Accurate Detection of Covid-19-Specific Nucleocapsid Protein in Clinical Serum Samples Using Modified Cleavable Mesoporous SiO2 Satellite-Enriched Carbon Dots

Cited by 3 publications

References 72 publications

Red/NIR C-dots: A perspective from carbon precursors, photoluminescence tuning and bioapplications

Red/NIR C-dots: A perspective from carbon precursors, photoluminescence tuning and bioapplications

Ratiometric fluorescence quantitation of amoxicillin based on CDs@Eu-MOFs incorporated 3D hydrogel using smartphone-assisted portable dual mode visual sensing

Fluorometric Sensors and Devices for Biomarkers

Contact Info

Product

Resources

About

Ultrasensitive Ratiometric Fluorescence Bioassay for Accurate Detection of Covid-19-Specific Nucleocapsid Protein in Clinical Serum Samples Using Modified Cleavable Mesoporous SiO₂ Satellite-Enriched Carbon Dots