Ultrasensitive Sensing of Volatile Organic Compounds Using a Cu‐Doped SnO₂‐NiO p‐n Heterostructure That Shows Significant Raman Enhancement**

Abstract

Surface enhanced Raman scattering (SERS) based on chemical mechanism (CM) attracts tremendous attention for great selectivity and stability.H owever,l ow enhancement factor (EF) limits its practical applications for trace detection.Here,an ovel sponge-like Cu-doping SnO 2 -NiO p-n semiconductor heterostructure (SnO 2 -NiO x /Cu), was first created as aCM-based SERS substrate with asignificant EF of 1.46 10 10 .T his remarkable EF was mainly attributed to the enhanced charge-separation efficacy of p-n heterojunction and charge transfer resonance resulted from Cu doping. Moreover,t he porous structure enriched the probe molecules, resulting in further SERS signals magnification. By immobilizing CuPc as an inner-reference element, SnO 2 -NiO x /Cu was developed as aSERS nose for selective recognition of multiple lung cancer related VOCs down to ppb level. The information of VOCs was recorded in ab arcode,d emonstrating practical potential of ad esktop SERS device for biomarker screening.

Simple Plasma Test Based on a MoSe2 SERS Platform for the Specific Diagnosis of Alzheimer’s Disease

“…(Figure S3). The EF is an important evaluation index of the SERS effect, and its calculation formula is as follows: EF = I SERS I bulk × N bulk N SERS …”

Semiconductor-based surface enhanced Raman scattering (SERS): from active materials to performance improvement

“…is also adopted to improve the SERS performance. Zhou et al synthesized Cu-doped SnO 2 -NiO semiconductor SERS substrate and achieved very high enhancement factor (1.46 × 10 10 ) 105 (Fig. 9c).…”

Flexible Two-Dimensional Vanadium Carbide MXene-Based Membranes with Ultra-Rapid Molecular Enrichment for Surface-Enhanced Raman Scattering

“…The SERS activity of noble-metal-free materials is mainly derived from the charge transfer (CT) between the material and the adsorbed molecule, namely the chemical mechanism (CM). , Compared with noble metal materials, noble-metal-free materials possess more plentiful physical and chemical properties, providing enormous possibilities for the optimization of SERS performances. In recent years, researchers have prepared a series of novel noble-metal-free SERS materials with excellent performances through optimizing the morphology, , stoichiometric ratio, , crystallinity, , and crystal orientation of non-noble metal materials, such as metal oxides, − transition metal dichalcogenides, , metal organic frameworks, , organic semiconductors, , etc. However, these enhancement strategies tend to focus on regulating the physical and chemical properties of noble-metal-free materials, while ignoring the improvement of SERS performances by molecular enrichment.…”