Ultrasonic-Assisted Extraction of the Botanical Dietary Supplement Resveratrol and Other Constituents of Polygonum cuspidatum

Abstract

The roots of Polygonum cuspidatum produce several phenolic compounds, including trans-resveratrol (1), trans-piceid (2), and emodin (3), and are a commercial source of the botanical dietary supplement 1. Ultrasonic-assisted extraction technology and conventional shaking extraction procedures were compared for the extraction of 1-3 from P. cuspidatum roots, using 50% ethanol as a food grade solvent. These compounds were extracted successfully, and their mass transfer coefficients were calculated by fitting the experimental results to a model derived from Fick's second law. The results indicated that ultrasonic-assisted extraction had higher mass transfer efficacies and extraction yields for 1-3 as compared with conventional shaking extraction. Under the extraction conditions used (extraction temperature 50 °C; ultrasonic power 150 W), yields of 3.5, 9.2, and 7.8 mg/g were obtained for 1-3, respectively.

Production of Resveratrol by Piceid Deglycosylation Using Cellulase

“…(including blueberry, bilberry, and cranberry), peanut and huzhang (Polygonum cuspidatum) [7][8][9]. In these foods, a glycosylated derivative of resveratrol, piceid (3,5,4 1 -trihydroxystilbene-3-O-β-D-glucopyranoside), is also present in good quantity [10].…”

Ultrasound-assisted extraction of resveratrol from functional foods: Cookies and jams

“…Furthermore, different studies on the ultrasonic extraction of resveratrol indicate that the optimal extraction temperature is between 50 and 70°C. Hence, in this study the temperature was fixed at 60°C as recommended in the literature [3,14] The design of experiment (DOE) matrix was established with a Resolution (R) of V + (full factorial) and therefore the design did not suffer from confounding of the main effects and two-variable interaction effects and, furthermore, the two-variable interaction effects were not confounded with each other [15]. The total design matrix consisted of 8 (2 3 ) runs ( Fig.…”

“…This compound is synthesized by plants as a means of protection against pathogenic attack, environmental stress, UV irradiation, fungal infections [2], the effects of ozone, heavy metal ions, and changes in climate (extreme cold) [3]. This active compound has important properties such as antioxidant, anti-inflammatory, analgesic, cardio-and neuro-protective, anti-aging, antitumor, and anticancer effects [4].…”

“…The results of some studies suggest that resveratrol-rich supplements are effective in slowing progressive dementia [6]. In recent years, resveratrol has become a dietary supplement in several countries [3] with a dose between 1 and 8 mg by tablet. However, the resveratrol present in some functional foods would be a more convenient source for regular consumers and functional foods that contain resveratrol are of increasing interest in the market [7].…”

“…Ultrasound-assisted extraction is an increasingly attractive approach due its inherent advantages; namely, high efficiency and reproducibility, ease of operation, and relatively short extraction time. The application of UAE therefore minimizes the degradation of bioactive compounds [3], reduces analysis costs, requires less laboratory work, and can produce high purity compounds in the extraction yield [8].…”