Ultrasonic properties in marrow-filled and water-filled bovine femoral trabecular bones <i>invitro</i>

Lee, Kang Il

doi:10.1121/1.4751989

Cited by 4 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Measurements of nBUA and SOS in human cancellous calcaneus / femur at 1 MHz suggest that replacing marrow with water has anywhere from no statistically significant effect on either parameter [22,112] to a mean decrease of nBUA of 5.6 dB/cmMHz [317] and a mean increase of SOS of 20-43 m/s [166,317]. Measurements in bovine cancellous femur at 500 kHz and 1 MHz suggest a mean decrease of nBUA of 2 -10 dB/cmMHz and mean increases of SOS of 35 -48 m/s [120,133,318]. Measurements in bovine tibia at 2.25 MHz suggest no significant change in either parameter [115].…”

Section: B the Effect Of Fluid Fillermentioning

confidence: 93%

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Wear

2020

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

View full text Add to dashboard Cite

Ultrasound is now a clinically-accepted modality in the management of osteoporosis. The most common commercial clinical devices assess fracture risk from measurements of attenuation and sound speed in cancellous bone. This review discusses fundamental mechanisms underlying the interaction between ultrasound and cancellous bone. Because of its two-phase structure (mineralized trabecular network embedded in soft tissue-marrow), its anisotropy, and its inhomogeneity, cancellous bone is more difficult to characterize than most soft tissues. Experimental data for the dependences of attenuation, sound speed, dispersion, and scattering on ultrasound frequency, bone mineral density, composition, microstructure, and mechanical properties are presented. The relative roles of absorption, scattering, and phase cancellation in determining attenuation measurements in vitro and in vivo are delineated. Common speed of sound metrics, which entail measurements of transit times of pulse leading edges (to avoid multipath interference), are greatly influenced by attenuation, dispersion, and system properties including center frequency and bandwidth. However, a theoretical model has been shown to be effective for correction for these confounding factors in vitro and in vivo. Theoretical and phantom models are presented to elucidate why cancellous bone exhibits negative dispersion, unlike soft tissue, which exhibits positive dispersion. Signal processing methods are presented for separating "fast" and "slow" waves (predicted by poro-elasticity theory and supported in cancellous bone) even when the two waves overlap in time and frequency domains. Models to explain dependences of scattering on frequency and mean trabecular thickness are presented and compared with measurements. Anisotropy, the effect of the fluid filler medium (marrow in vivo or water in vitro), phantoms, computational modeling of ultrasound propagation, acoustic microscopy, and nonlinear properties in cancellous bone are also discussed.

show abstract

Section: B the Effect Of Fluid Fillermentioning

confidence: 93%

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Wear

2020

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

View full text Add to dashboard Cite

show abstract

Ultrasonic wave properties of human bone marrow in elderly people

Ueda

Kawasaki

Matsukawa

et al. 2015

2015 6th European Symposium on Ultrasonic Characterization of Bone

View full text Add to dashboard Cite

Dependences of ultrasonic properties on frequency and trabecular spacing in trabecular-bone-mimicking phantoms

Lee¹

2015

The Journal of the Acoustical Society of America

Self Cite

View full text Add to dashboard Cite

The dependences of ultrasonic properties on the frequency and the trabecular spacing were investigated in 20 trabecular-bone-mimicking phantoms consisting of cellular copper foams. The strong slow waves were consistently observed in the signals transmitted through all of the phantoms. The frequency-dependent phase velocity and attenuation coefficient of the slow wave were measured at frequencies from 0.7 to 1.3 MHz. The phase velocity decreased approximately linearly with increasing frequency while the attenuation coefficients increased with increasing frequency. The phase velocity increased monotonically with increasing trabecular spacing from 1337 to 2931 μm while the attenuation coefficient decreased with increasing spacing.

show abstract

Ultrasonic properties in marrow-filled and water-filled bovine femoral trabecular bones invitro

Cited by 4 publications

References 19 publications

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Mechanisms of Interaction of Ultrasound With Cancellous Bone: A Review

Ultrasonic wave properties of human bone marrow in elderly people

Dependences of ultrasonic properties on frequency and trabecular spacing in trabecular-bone-mimicking phantoms

Contact Info

Product

Resources

About