Ultrasonically Propelled Micro‐ and Nanorobots

Li, Jinhua; Mayorga‐Martinez, Carmen C.; Ohl, Claus‐Dieter; Pumera, Martin

doi:10.1002/adfm.202102265

Cited by 80 publications

(57 citation statements)

References 128 publications

(238 reference statements)

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“…Following that, this paper identifies important transcription prospective implications of ultrasound-mechanical functioning micro-and nanorobots in medicinal, ecological, and other disciplines. Finally, this paper provides a perspective on the development of ultrasound-driven nanorobots [13].…”

Section: Related Workmentioning

confidence: 99%

“…e OD 600 from equally bacterial isolates is measured at every hour for first 6 hrs, then each 2 hours again until research ended. Parallel to this, 50-l dilutions from both bacteria specimens are obtained and centrifugated (13,200 rpm, 5 min), with the suspension being centrifuged saved to complete the hemolytic experiment (5% RBC solutions plus toxin, 30 min at 37 °C). Comparative hemolysis rates are computed using the transmittance acquired from 5% RBC solutions deionized for 5 minutes and 100% hemolysis.…”

Section: Concurrent Bacteria Removal and Pft Of Bacteriamentioning

confidence: 99%

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Nanorobots with Hybrid Biomembranes for Simultaneous Degradation of Toxic Microorganism

Refaai

Manjunatha

Radjarejesri³

et al. 2022

Advances in Materials Science and Engineering

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Nanorobotics is a modern technological sector that creates robots with elements that are close to or near the nanoscale scale of such a nanometer. To be more specific, nanorobotics has been the nanotechnology approach to designing and creating nanorobots. Also, with the fast growth of robotics technology, developing biomaterials micro- or nanorobots, which convert biological concepts into a robotic device, grows progressively vital. This proposes the development, manufacturing, and testing of a dual–cell membrane–functionalized nanorobot for multifunctional biological threat component elimination, with a focus on the simultaneous targeted and neutralization of the pathogenic bacteria and toxins. Ultrasound-propelled biomaterials nanorobots comprised of the gold nanostructures wrapped in a combination of platelet (PL) and Red Blood Cell (RBC) layers were developed. Biohybrid micro- and nanorobots were small machines that combine biological and artificial elements. They may benefit from onboard actuators, detection, management, and deployment of a variety in medical functions. These hybrid cell walls consist of a variety of structural proteins involved in living organism RBCs and PLs, which provide nanorobots with either a quantity of the appealing biological functionality, with bonding and adhesion to the PL-adhering pathogenic organisms (for example, staphylococcus bacteria) but also neutralization of the pore-forming toxins (e.g., toxin). Furthermore, the biomaterials nanorobots demonstrated quick and efficient extended sonic propulsion for total blood with really no visible bacterial growth and mirrored the movements of genuine cell separation. This propulsion improved the robots’ bonding and detoxifying efficacy against infections and poisons. Overall, combining this diversified physiological activity of hybrid cellular tissue with the energy propulsion of such robotic systems contributed to the dynamic robotics scheme for effective separation and synchronous elimination of various living risks, a significant step towards to development of a broad-spectrum detoxifying robotic framework.

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Section: Related Workmentioning

confidence: 99%

Section: Concurrent Bacteria Removal and Pft Of Bacteriamentioning

confidence: 99%

Nanorobots with Hybrid Biomembranes for Simultaneous Degradation of Toxic Microorganism

Refaai

Manjunatha

Radjarejesri³

et al. 2022

Advances in Materials Science and Engineering

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“…After the idea of nano- and micromachines that carry out medical tasks inside a patient’s body has been a dream for several decades, the progress in nanotechnology at the end of the last century made the fabrication of motile nano- and microparticles (so-called active particles) possible. − During the last two decades, a large number of artificial motile nano- and microparticles that utilize various mechanisms for propulsion have been developed, ,− and fascinating future applications of these particles have been envisaged in fields like medicine, − where they could be used for targeted drug delivery, − materials science, − where they could be used to form active crystals − and other new types of matter, and environmental care. ,− …”

Section: Introductionmentioning

confidence: 99%

Acoustic Propulsion of Nano- and Microcones: Dependence on the Viscosity of the Surrounding Fluid

Voß

Wittkowski

2022

Langmuir

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This article investigates how the acoustic propulsion of cone-shaped colloidal particles that are exposed to a traveling ultrasound wave depends on the viscosity of the fluid surrounding the particles. Using acoustofluidic computer simulations, we found that the propulsion of such nano-and microcones decreases strongly and even changes sign for increasing shear viscosity. In contrast, we found only a weak dependence of the propulsion on the bulk viscosity. The obtained results are in line with the findings of previous theoretical and experimental studies.

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“…The detailed categories, application scenarios, advantages, and limitations of different actuation methods have been comprehensively summarized by many researchers. Readers can refer to review articles [2,34,[50][51][52][53][54][55][56][57][58][59][60] and corresponding research articles given in Table 1 for more technical content.…”

Section: Open-loop Control Of Microrobots 21 Actuation Strategies Of ...mentioning

confidence: 99%

Control and Autonomy of Microrobots: Recent Progress and Perspective

Jiang

Yang

Ferreira

et al. 2022

Advanced Intelligent Systems

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After decades of development, microrobots have exhibited great application potential in the biomedical field, such as minimally invasive surgery, drug delivery, and bio‐sensing. Compared with conventional medical robotic systems, microrobots may be capable of reaching more narrow and vulnerable regions in the human body with minimal damage. However, limited by the small scale of microrobots, microprocessors, power supplies, and sensors can hardly be integrated on‐board. Thus, new strategies for the actuation and feedback for microrobots need to be explored. Furthermore, the open‐loop control method accomplished by operators may lack accuracy, and long‐duration operation could bring a severe physical challenge in many applications. Consequently, the automatic control of microrobots with the aid of control theories is developed to improve the control efficiency and precision. To further promote the automation level of microrobots, machine learning algorithms are expected to provide a solution to let microrobots adapt to more dynamic environments and undertake more complex medical tasks. Herein, a systematic introduction of the manipulation of microrobots from open‐loop to closed‐loop control is given in this review. It is envisioned that microrobots will play an important role in future biomedical applications.

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Ultrasonically Propelled Micro‐ and Nanorobots

Cited by 80 publications

References 128 publications

Nanorobots with Hybrid Biomembranes for Simultaneous Degradation of Toxic Microorganism

Nanorobots with Hybrid Biomembranes for Simultaneous Degradation of Toxic Microorganism

Acoustic Propulsion of Nano- and Microcones: Dependence on the Viscosity of the Surrounding Fluid

Control and Autonomy of Microrobots: Recent Progress and Perspective

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