Ultrasonication-assisted green synthesis and characterization of gold nanoparticles from Nothapodytes foetida: An assessment of their antioxidant, antibacterial, anticancer and wound healing potential

Susanna, Deepti; Balakrishnan, Raj Mohan; Ettiyappan, Jagadeeshbabu Ponnan

doi:10.1016/j.jddst.2023.104740

Cited by 16 publications

(5 citation statements)

References 120 publications

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“…The FTIR spectroscopy provides insightful details about the molecular interactions within the synthesized gold nanoparticles (Figure ( 5)). The observed shift in the O-H absorption band from 3438 to 3428 cm − 1 suggests a strong interaction between the phenolic compounds in the Halpeh plant extract and the surface of the gold nanoparticles [30]. This shift could indicate the formation of a new chemical environment or bond formation, which stabilizes the nanoparticles.…”

Section: Ftir Analysis Resultsmentioning

confidence: 95%

Halpeh Extract-Derived Gold Nanoparticles: A Dual Force Against Microbes and for Phytochemical Enhancement

Dahaz,

Asadi,

Lashgari

2024

Preprint

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The increasing resistance of pathogenic microorganisms to conventional antibiotics has led to a growing interest in alternative antimicrobial agents. In this study, the antimicrobial activity (antibacterial and antifungal) of aqueous and methanolic extracts of Halpeh plant and gold nanoparticles synthesized using the extract of this plant was investigated. Additionally, the effect of different concentrations of synthesized gold nanoparticles on the phytochemical properties (antioxidant and reducing ability) of Halpeh plant extract was examined. The results of UV-Vis (Ultraviolet-Visible Spectroscopy), XRD (X-Ray Diffraction Analysis), TEM (Transmission Electron Microscopy), SEM (Scanning Electron Microscopy), and FTIR (Fourier Transform Infrared Spectroscopy) tests on gold nanoparticles confirmed their synthesis. SEM and TEM images showed that the gold nanoparticles were spherical in shape with an average size of 22.89 nm. According to the results, the methanolic extract exhibited significantly higher antibacterial and antifungal activity compared to the aqueous extract, with the maximum inhibition zone diameters observed for Escherichia coli (14 mm) and Aspergillus niger (15 mm). Moreover, the antimicrobial activity of gold nanoparticles showed that these nanoparticles have relatively good ability to inhibit gram-negative bacteria, with the largest inhibition zone diameters observed for Escherichia coli (18 mm) and Aspergillus niger (20 mm). The antioxidant and reducing power activity (phenolic flavonoids content) of Halpeh plant extract treated with different concentrations of synthesized gold nanoparticles increased with increasing nanoparticle concentrations up to 60 ppm (IC50 = 9.94 µg/ml and reducing power = 16.85 mMFe2+/mg sample), and decreased at higher concentrations.

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Section: Ftir Analysis Resultsmentioning

confidence: 95%

Halpeh Extract-Derived Gold Nanoparticles: A Dual Force Against Microbes and for Phytochemical Enhancement

Dahaz,

Asadi,

Lashgari

2024

Preprint

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“…Plants have a wide variety of phytochemical compounds (polyphenols, avonoids, terpenes, saponins, terpenoids, alkaloids, tannins, saccharides, vitamins, chelating proteins etc.) that have an antioxidant effect [11][12]. Since the rst article on the green synthesis of AgNPs via the alfalfa (Medicago sativa) plant published by Gardea-Torresdey et al in 2003, the mechanism of silver nanoparticle synthesis via plant extracts remains a mystery [13][14].…”

Section: Introductionmentioning

confidence: 99%

“…Since the rst article on the green synthesis of AgNPs via the alfalfa (Medicago sativa) plant published by Gardea-Torresdey et al in 2003, the mechanism of silver nanoparticle synthesis via plant extracts remains a mystery [13][14]. Studies have shown that the formation mechanism of silver nanoparticles depends on the type of plant extract used as a reducing agent, and also that many components present in the plant are responsible for the formation of metal nanoparticles [11,15]. Also various studies show that silver ions in plant material extracts are formed in plants by reduction via proteins [16], polysaccharides [17], vitamins [18] and secondary metabolites [19].…”

Section: Introductionmentioning

confidence: 99%

Green Synthesis of Silver Nanoparticles and Comprehensive Characterization for Biomedical Applications

Doğan,

Kaya,

Solak

2024

Preprint

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This study details the preparation and extraction process of Origanum onites plant extract collected from Denizli, Turkey. The leaves were meticulously cleaned, dried, and ground before undergoing extraction in a water-ethanol solution using a Soxhlet Apparatus at 100 ºC for 6 h. The resulting extract was evaporated and stored for future use at + 4°C. Afterwards, the extract was utilized in the green synthesis of silver nanoparticles by adding it to a solution of silver nitrate. The impact of temperature on the synthesis of silver nanoparticles was explored across various temperature values (30 ºC, 60 ºC, and 90 ºC). Furthermore, the influence of reaction time on silver nanoparticle formation was investigated at the determined optimum temperature, with examination periods set at 60, 120, and 180 minutes. The influence of temperature on the antioxidant activity and cytotoxicity of the synthesized nanoparticles has been explored across three distinct temperature values. Characterization of the Silver Nanoparticles (AgNPs) included UV–Vis Spectrophotometry for surface plasmon resonance, Scanning Electron Microscopy (SEM) for morphological analysis, Energy Dispersive X-ray analysis (EDX) for elemental composition, Particle size distribution and Fourier-transform infrared spectroscopy (FT-IR) spectroscopy for interpreting chemical bonds and functional groups.

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“…16–19 Thus, biogenic Ag-NPs synthesized using plant extracts have been widely reported in the literature. 17,20–22 For instance, Gomaa 17 synthesized biogenic Ag-NPs using onion extracts as both reducing and antimicrobial agents against Staphylococcus aureus ( S. aureus ) , Escherichia coli ( E. coli ) and fungi. In a related study by Sekar et al , 18 biogenic Ag-NPs from Allium cepa were effective against not only foodborne illness-causing pathogens such as Bacillus sp.…”

Section: Introductionmentioning

confidence: 99%

“…24–26 In particular, it facilitates the formation of a homogeneously distributed stable suspension, smaller Ag-NP size, faster reaction rate, time-efficiency, cost effectiveness and tuneability. 27 Susanna et al 21 used an ultrasonic–biogenic approach to synthesize spherical (5 and 30 nm) gold nanoparticles for antioxidant, antibacterial, anticancer and wound healing applications. Meanwhile, Ahmada et al 28 synthesized biogenic Ag-NPs using ultrasound and cinnamon extract for antimicrobial application.…”

Section: Introductionmentioning

confidence: 99%

Ultrasonic–biogenic synthesis of silver on anodized aluminum with superior antibacterial properties

Agbe,

Sarkar,

Chen

et al. 2023

Mater. Adv.

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Ultrasonication-assisted green synthesis and characterization of gold nanoparticles from Nothapodytes foetida: An assessment of their antioxidant, antibacterial, anticancer and wound healing potential

Cited by 16 publications

References 120 publications

Halpeh Extract-Derived Gold Nanoparticles: A Dual Force Against Microbes and for Phytochemical Enhancement

Halpeh Extract-Derived Gold Nanoparticles: A Dual Force Against Microbes and for Phytochemical Enhancement

Green Synthesis of Silver Nanoparticles and Comprehensive Characterization for Biomedical Applications

Ultrasonic–biogenic synthesis of silver on anodized aluminum with superior antibacterial properties

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