Ultrasonographic Diagnosis of Lipofibromatous Hamartoma of Median Nerve in a Twenty-Seven-Year-Old Woman

Afshar, Ahmadreza; Omid, Assadzadeh; Mohammadi, Afshin

doi:10.5812/iranjradiol.11270

Cited by 10 publications

(6 citation statements)

References 11 publications

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“…Rare benign lesions affecting peripheral nerves are perineurioma (differentiated perineurial cells inside or outside a nerve), intraneural lipoma and/or lipofibromatous hamartoma (fibrofatty tumor characterized by the proliferation of mature adipocytes within the epineurium and the perineurium of the peripheral nerves), [7][8][9] and intraneural vascular malformations. 10,11 These are called purely benign because they have no predilection for malignant transformation.…”

Section: Purely Benign Lesionsmentioning

confidence: 99%

Nerve Tumors: What the MSK Radiologist Should Know

Tagliafico

Isaac

Bignotti

et al. 2019

Semin Musculoskelet Radiol

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Nerve tumors are rare and heterogeneous soft tissue tumors arising from a peripheral nerve or showing nerve sheath differentiation. In a radiologic setting it is necessary to recognize soft tissue lesions that are of neural origin, their association with a peripheral nerve, and whether they are a true tumor or a so-called pseudotumor such as a neuroma, fibrolipoma, or peripheral nerve sheath ganglion. Ultrasound (US) and magnetic resonance imaging are the best modalities to characterize these lesions. US can be used to guide biopsy in difficult and uncertain cases when the lesion is either indeterminate or possibly malignant. At present, no single imaging feature or reproducible criteria, or a combination, can differentiate reliably between a neurofibroma and a schwannoma or discriminate with certainty between benign and malignant neurogenic tumors. Adequate imaging and consultation with a nerve tumors/sarcoma unit is advised.

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Section: Purely Benign Lesionsmentioning

confidence: 99%

Nerve Tumors: What the MSK Radiologist Should Know

Tagliafico

Isaac

Bignotti

et al. 2019

Semin Musculoskelet Radiol

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“…LFH can be found in various peripheral nerves, but the median nerve is most commonly affected in the upper extremity. LFH is characterized by slow progression due to the proliferation of mature adipose cells within the epineurium and perineurium of a peripheral nerve [1][2][3][4][5][6]. LFH of the median nerve can be asymptomatic or present with pain, swelling, numbness, paraesthesia, or carpal tunnel syndrome [1,4,7,8].…”

Section: Introductionmentioning

confidence: 99%

Lipofibromatous Hamartoma of the Median Nerve: A Case Report

Elbayer¹,

Alharami²,

Elhessy³

2023

Cureus

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Lipofibromatous hamartoma (LFH) is a rare benign peripheral nerve tumor. The median nerve (MN) is most commonly affected in the upper extremity. We report a case of a 39-year-old male with LFH of the median nerve presented with swelling and symptoms of carpal tunnel syndrome treated successfully with decompression. LFH is reported with various descriptions because of the proliferative nature of its adipocytes and the fibrofatty infiltration within the peripheral nerves. Swelling around the volar aspect of the wrist remains the most frequent presentation of LFH. Surgical decompression without tumor resection can result in symptom improvement. In addition, post-decompression nerve coverage can be a solution to improve the residual hyperesthesia symptoms.

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“…Complete excision of neural masses is often more difficult in comparison to nonneural masses. 29 Malignant tumors as a cause of median nerve compression is extremely rare. Therefore, treatment should be adapted to the national guidelines and with multidisciplinary consultation.…”

Section: Discussionmentioning

confidence: 99%

Rare Tumors Causing Median Nerve Compression in Adults—A Narrative Review

et al. 2022

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The median nerve can be compressed due to a tumor along the course of the median nerve, causing typical compression symptoms or even persistence or recurrence after an operation. The aim of this review is to provide a comprehensive overview of rare tumors described in recent publications that cause median nerve compression and to evaluate treatment options.The PubMed, Embase, and Web of Science databases were searched for studies describing median nerve compression due to a tumor in adults, published from the year 2000 and written in English. From 94 studies, information of approximately 100 patients have been obtained. Results The rare tumors causing compression were in 32 patients located at the carpal tunnel, in 21 cases in the palm of the hand, and 28 proximal from the carpal tunnel. In the other cases the compression site extended over a longer trajectory. There were 37 different histological types of lesions. Complete resection of the tumor was possible in 58 cases. A total of 8 patients presented for the second time after receiving initial therapy. During follow-up, three cases of recurrence were reported with a mean follow-up period of 11 months.The most common published cause of median nerve compression is the lipofibromatous hamartoma. Besides the typical sensory and motor symptoms of median nerve compression, a thorough physical examination of the complete upper extremity is necessary to find any swelling or triggering that might raise suspicion of the presence of a tumor.

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Ultrasonographic Diagnosis of Lipofibromatous Hamartoma of Median Nerve in a Twenty-Seven-Year-Old Woman

Cited by 10 publications

References 11 publications

Nerve Tumors: What the MSK Radiologist Should Know

Nerve Tumors: What the MSK Radiologist Should Know

Lipofibromatous Hamartoma of the Median Nerve: A Case Report

Rare Tumors Causing Median Nerve Compression in Adults—A Narrative Review

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